DataVXAdvanced MaterialsPaper
journal article·2014-12

Two‐Photon Excitation of Porphyrin‐Functionalized Porous Silicon Nanoparticles for Photodynamic Therapy

Emilie Secret, Marie Maynadier, Audrey Gallud, Arnaud Chaix, Elise Bouffard, Magali Gary‐Bobo, Nathalie Marcotte, Olivier Mongin, Khaled El Cheikh, Vincent Hugues, Mélanie Auffan, Céline Frochot, Alain Morère, Philippe Maillard, Mireille Blanchard‐Desce, Michael J. Sailor, Marcel Garcia, Jean‐Olivier Durand, Frédérique Cunin

Advanced Materials· Volume 26· Issue 45
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Source abstract

Abstract

Porous silicon nanoparticles (pSiNPs) act as a sensitizer for the 2-photon excitation of a pendant porphyrin using NIR laser light, for imaging and photodynamic therapy. Mannose-functionalized pSiNPs can be vectorized to MCF-7 human breast cancer cells through a mannose receptor-mediated endocytosis mechanism to provide a 3-fold enhancement of the 2-photon PDT effect. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Silicon Nanostructures and Photoluminescence · Nanowire Synthesis and Applications · Nanoplatforms for cancer theranostics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Institut Charles Gerhardt Montpellier UMR 5253 CNRS‐ENSCM‐UM2‐UM1 Ecole Nationale Supérieure de Chimie de Montpellier 8 rue de l'Ecole Normale 34296 Montpellier France

CNRS, GDR 3049 Photomed France

Institut des Biomolecules Max Mousseron UMR 5247 CNRS‐UM1‐UM2 15 Avenue Charles Flahault BP 14491 34093 Montpellier Cedex 05 France

Institut des Sciences Chimiques de Rennes, CNRS UMR 6226 Université Rennes 1, Campus de Beaulieu Université Rennes 1 35042 Rennes Cedex France

Université Bordeaux 1 Institut des Sciences Moléculaires, UMR CNRS 5255 351 Cours de la Libération F‐33405 Talence Cedex France

CEREGE, UMR 7330 CNRS AMU, Europole de l'arbois BP80 13545 Aix en Provence France

Université de Lorraine Laboratoire Réactions et Génie des Procédés (LRGP), UMR 7274 Nancy F‐54000 France

CNRS, LRGP, UMR 7274 Nancy F‐54000 France

UMR 176 CNRS/Institut Curie Institut Curie, Bat. 110, Université Paris‐Sud, F‐91405 Orsay, France – Institut Curie, Section de Recherches Centre Universitaire, Université Paris‐Sud F‐91405 Orsay France

University of California, San Diego Department of Chemistry and Biochemistry 9500 Gilman Drive, m/c 0358 La Jolla CA 92093‐0358 USA

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