journal article·2017-04

Virus‐Mimetic Fusogenic Exosomes for Direct Delivery of Integral Membrane Proteins to Target Cell Membranes

Yoosoo Yang, Yeonsun Hong, Gi‐Hoon Nam, Jin Hwa Chung, Eunee Koh, In‐San Kim

Advanced Materials· Volume 29· Issue 13
Publisher page

Abstract

An efficient system for direct delivery of integral membrane proteins is successfully developed using a new biocompatible exosome-based platform. Fusogenic exosomes harboring viral fusogen, vascular stomatitis virus (VSV)-G protein, can fuse with and modify plasma membranes in a process called “membrane editing.” This can facilitate the transfer of biologically active membrane proteins into the target cell membranes both in vitro and in vivo. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Extracellular vesicles in disease · RNA Interference and Gene Delivery · Viral Infections and Vectors

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Biomedical Research Institute Korea Institute of Science and Technology (KIST) Seoul 02792 Republic of Korea

KU‐KIST Graduate School of Converging Science and Technology Korea University Seoul 02841 Republic of Korea

Bio‐Imaging Center Asan Institute for Life Science Asan Medical Center Seoul 05505 Republic of Korea

Funding

Ministry of Health and Welfare · Korea Institute of Science and Technology

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