journal article·2010-11-24Open access

Temperature‐Responsive Polymer Brushes Switching from Bactericidal to Cell‐Repellent

Xavier Laloyaux, Emilie Fautré, Thomas Blin, Viswas Purohit, Jérôme Leprince, Thierry Jouenne, Alain M. Jonas, Karine Glinel

Advanced Materials· Volume 22· Issue 44

Abstract

The composition of temperature-responsive copolymer brushes based on oligo(ethylene glycol) methacrylates is tuned to obtain a collapse temperature of ∼35 °C. The chains are grafted by antibacterial magainin I peptide, whose activity is tested at different temperatures against various bacteria. The brushes switch from bactericidal to cell-repellent below and slightly above 35 °C, respectively, due to the progressive vertical collapse of the brush. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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Research context

OpenAlex topics: Bacteriophages and microbial interactions · Polymer Surface Interaction Studies · Bacterial biofilms and quorum sensing

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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