DataVXAdvanced Functional MaterialsPaper
journal article·2026-01Open access

Rapid Single‐Cell Proteomics Using Nanoconfined Enzyme Reactors on a Microscale Digital Microfluidics Platform (Adv. Funct. Mater. 2/2026)

Menglei Zhao, Hang Li, Zongliang Guo, Haobing Liu, Jiaxi Peng, Yechen Hu, Bin Fu, Boyu Li, Liyuan Guo, Rongxin Fu, Yao Lu, Pengfei Song, Wei Xu, Akos Vertes, Huikai Xie, Shuailong Zhang

Advanced Functional Materials· Volume 36· Issue 2
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Source abstract

Abstract

Rapid Single-Cell Proteomics This cover illustrates the integration of a digital microfluidics platform with a nanoconfined enzyme reactor for rapid single-cell proteomics sample preparation, followed by single-cell subtype classification using mass spectrometry. More information can be found in the Research Article by Hang Li, Shuailong Zhang, and co-workers (10.1002/adfm.202502142).
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Research context

Nanomaterials

OpenAlex topics: Electrowetting and Microfluidic Technologies · Innovative Microfluidic and Catalytic Techniques Innovation · Microfluidic and Bio-sensing Technologies

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Affiliations

Beijing Advanced Innovation Center for Intelligent Robots and Systems School of Mechatronical Engineering Beijing Institute of Technology Beijing 100081 China

Zhengzhou Research Institute Beijing Institute of Technology Zhengzhou 450000 China

School of Medical Technology Beijing Institute of Technology Beijing 100081 China

Engineering Research Center of Integrated Acousto‐opto‐electronic Microsystems (Ministry of Education of China) Chongqing Institute of Microelectronics and Microsystems Beijing Institute of Technology Chongqing 400000 China

Department of Chemistry University of Toronto 80 St George Street Toronto ON M5S 3H6 Canada

State Key Laboratory of Medical Proteomics Beijing Proteome Research Center National Center for Protein Sciences (Beijing) Beijing Institute of Lifeomics Beijing 102206 China

School of Integrated Circuits and Electronics Beijing Institute of Technology Beijing 100081 China

School of Advanced Technology Xi'an Jiaotong‐Liverpool University Suzhou 215000 China

Department of Chemistry The George Washington University Washington DC 20052 USA

References

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