Cell‐Delivering Injectable Hydrogels with Tunable Microporous Structures Improve Therapeutic Efficacy for Volumetric Muscle Loss (Adv. Funct. Mater. 47/2025)
Source abstract
Abstract
Cell-Delivering Injectable Hydrogels In their Research Article (10.1002/adfm.202508302), Akihiro Nishiguchi and co-workers present an injectable hydrogel with tunable microporosity to improve cell delivery for volumetric muscle loss treatment. Mesenchymal stem cells encapsulated in porous hydrogels significantly promote the spreading, proliferation, and cytokine secretion of mesenchymal stem cells. This hydrogel improves graft survival and muscle regeneration, offering the promise for cell transplantation applications.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Tissue Engineering and Regenerative Medicine · Muscle Physiology and Disorders · Electrospun Nanofibers in Biomedical Applications
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Affiliations
Graduate School of Advanced Engineering Tokyo University of Science 6‐3‐1 Niijuku, Katsushika‐ku Tokyo 125–8585 Japan
Biomaterials Field Research Center for Macromolecules and Biomaterials National Institute for Materials Science 1‐1 Namiki Tsukuba Ibaraki 305‐0044 Japan
References
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