Surface or Luminal? Decoding Tumor Extracellular Vesicle Logic for Functional Insight and Therapeutic Reprogramming (Adv. Funct. Mater. 51/2025)
Source abstract
Abstract
Tumor Extracellular Vesicle Logic In their Research Article (10.1002/adfm.202521108), Chi-An Cheng and co-workers introduce a nanoscale transformation, as tumor extracellular vesicles (EVs) travel from heterogeneous danger to homogeneous cure. This cover art illustrates the journey of the EV Bimodal Functional Regulator (eBFR): CLEAR purges hidden oncogenic cargo, SWITCHER isolates surface-defined EV subtypes, and eSimoa quantifies spatial protein signatures—reprogramming tumor EVs into safe, pure, and thousands-fold drug-loaded couriers for precision medicine.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Extracellular vesicles in disease · Nanoplatforms for cancer theranostics · interferon and immune responses
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
School of Pharmacy College of Medicine National Taiwan University Taipei 10050 Taiwan
Department of Medicine College of Medicine National Taiwan University Taipei 10050 Taiwan
Graduate Institute of Immunology College of Medicine National Taiwan University Taipei 10050 Taiwan
References
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