DataVXAdvanced Functional MaterialsPaper
journal article·2024-08Open access

Silk Sericin is a Potent, Multifunctional Biomaterial for Endothelialization of Tissue‐Engineered Heart Valves (Adv. Funct. Mater. 32/2024)

Yu Song, Huifang Wang, Chuting Hu, Jia Liu, Weihua Qiao, Lei Huang, Nianguo Dong, Lin Wang

Advanced Functional Materials· Volume 34· Issue 32
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Source abstract

Abstract

Silk Sericin In article number 2315826, Nianguo Dong, Lin Wang, and co-workers present a silk sericin-modified decellularized heart valve that effectively prevents platelet adhesion and activation, while promoting endothelial cell adhesion, growth, and function, which results in rapid in vivo endothelialization. These highlight its significant potential for treating heart valve diseases and enhance our understanding of sericin's biological activity, as well as providing a theoretical foundation for its broad application in the biomedical field.
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Research context

Biomaterials

OpenAlex topics: Silk-based biomaterials and applications · Electrospun Nanofibers in Biomedical Applications · Bone Tissue Engineering Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Research Center for Tissue Engineering and Regenerative Medicine Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China

Hubei Key Laboratory of Regenerative Medicine and Multi‐disciplinary Translational Research Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China

Hubei Provincial Engineering Research Center of Clinical Laboratory and Active Health Smart Equipment Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China

Department of Clinical Laboratory Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China

Department of Cardiovascular Surgery Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China

References

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