DataVXAdvanced Functional MaterialsPaper
journal article·2022-11Open access

Free‐Blockage Mesoporous Silica Nanoparticles Loaded with Cerium Oxide as ROS‐Responsive and ROS‐Scavenging Nanomedicine (Adv. Funct. Mater. 46/2022)

Olha Purikova, Ihor Tkachenko, Břetislav Šmíd, Kateřina Veltruská, Thu Ngan Dinhová, Maryna Vorokhta, Vladimír Kopecký, Lenka Hanyková, Xiaohui Ju

Advanced Functional Materials· Volume 32· Issue 46
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Source abstract

Abstract

Mesoporous Materials In article number 2208316, Xiaohui Ju and co-workers report the design of free-blockage reactive oxygen species (ROS)-responsive mesoporous silica nanoparticles (MSNs) as potential drug delivery systems. Methyl sulfide units are functionalized onto MSNs through co-condensation or grafting pathways. In an ROS-rich environment, the nanocarriers undergo structure and polarity changes and release cargo of cerium oxide nanoparticles to scavenge excessive ROS related to pathological conditions.
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Research context

Nanomaterials

OpenAlex topics: Advanced Nanomaterials in Catalysis · Dendrimers and Hyperbranched Polymers · Nanomaterials for catalytic reactions

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Affiliations

Department of Surface and Plasma Science Faculty of Mathematics and Physics Charles University V Holešovičkách 747/2, Prague 8 CZ‐180 00 Prague Czech Republic

Institute of Macromolecular Chemistry National Academy of Sciences of Ukraine Kharkivske Shosse 48 Kyiv 02160 Ukraine

Department of Geochemistry Institute of Rock Structure and Mechanics Czech Academy of Sciences V Holešovičkách 94/41, Prague 8 CZ‐182 09 Prague Czech Republic

Institute of Physics Faculty of Mathematics and Physics Charles University Ke Karlovu 2026/5, Prague 2 CZ‐121 16 Prague Czech Republic

Department of Macromolecular Physics Faculty of Mathematics and Physics Charles University V Holešovičkách 747/2, Prague 8 CZ‐180 00 Prague Czech Republic

References

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