journal article·2022-09-05Open access

A preliminary study on the reactive suspension approach to create bioactive polymer nanocomposites for dental applications

Department of Mechanical Engineering, Kumaraguru College of Technology, Coimbatore - 641049, Tamil Nadu, India, K. K. Arun, S. Rajeshkannan, Department of Electronics and Communication Engineering, St. Joseph’s College of Engineering, OMR, Chennai - 600119, Tamil Nadu, India., P. Ezhilarasi, Department of Electronics and Communication Engineering, St. Joseph’s College of Engineering, OMR, Chennai - 600119, Tamil Nadu, India., L. Natrayan, Department of Mechanical Engineering, Saveetha School of Engineering, SIMATS, Chennai, Tamil Nadu, India.

Abstract

The modified chemical particle with appropriate combination agents possesses a lesser surface and the organic matrix gives more compatibility with the unprocessed matrix, is a typical strategy for limiting agglomeration problems. The limited time processing was the main sign of the chemical modification and particle purification. The production of nanoparticles directly inside the organic matrix is an alternate technique in situ approach. The present studies focused to make a new nanocomposites matrix with powder and liquid phase PMMA and hydroxyethyl methacrylate and it is processed by in-situ method to compose the hydroxyapatite nanoparticles of (Ca10(PO4)6(OH)2. Therefore reactive suspension approach was utilized in this study. During the in-situ process, the precursors like ammonium dihydrogen and calcium nitrate tetrahydrate are used. When the combinations of HA with the influence of the HEMA agent. These precursors and the agents composed the hybrid material with even dispersion. Due to maximum phase interrelations were achieved between the dead filler and polymer matrix base. HA is an inorganic phase that is osteogenic and osteoconductive, comparable to bone-based minerals. Similarly, it promotes polymer-based composites from bioactivity to enhance bone regeneration. The structure and morphology characteristics of PMMA, hydroxyethyl methacrylate and HA processed composites are examined in this work. The mechanical characteristics of the composites are measured in the combinational mode of compression and flexural. Then the bioactivity is investigated by submerging into the simulated bodily fluid (SBF). The mixing among the HA and polymer reduces the water sorption values significantly. After soaking in simulated bodily fluid, the surface of the HA generation was verified into the bioactivity of the processes composites.
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Research context

OpenAlex topics: Bone Tissue Engineering Materials · Dental materials and restorations · biodegradable polymer synthesis and properties

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References (31)

Show source-provided references
1. [1] L. Cheng, X. Zhou, H. Zhong, X. Deng, Q. Cai and X. Yang, Mater. Sci. Eng. C Mater. Biol. Appl., 2014, 34, 262-269; https://doi.org/10.1016/j.msec.2013.09.02010.1016/j.msec.2013.09.020 ↗
2. [2] X. Y. Zhang, X. J. Zhang, Z. L. Huang, B. S. Zhu and R. R. Chen, Dent. Mater. J., 2014, 33, 141-146; https://doi.org/10.4012/dmj.2013-05410.4012/dmj.2013-054 ↗
3. [3] N. Kojima, M. Yamada, A. Paranjpe, N. Tsukimura, K. Kubo, A. Jewett and T. Ogawa, Dent. Mater., 2008, 24, 1686-1693; https://doi.org/10.1016/j.dental.2008.04.00810.1016/j.dental.2008.04.008 ↗
4. [4] W. Yu, X. Wang, Q. Tang, M. Guo and J. Zhao, J. Mech. Behav. Biomed. Mater., 2014, 32, 192-197; https://doi.org/10.1016/j.jmbbm.2014.01.00310.1016/j.jmbbm.2014.01.003 ↗
5. [5] I. N. Safi, J. Baghdad Coll. Dent., 2014, 26, 37-41; https://doi.org/10.12816/001516210.12816/0015162 ↗
6. [6] J. C. Zhang, J. Liao, A. C. Mo, Y. B. Li, J. D. Li and X. J. Wang, Appl. Surf. Sci., 2008, 255, 328-330; https://doi.org/10.1016/j.apsusc.2008.06.12710.1016/j.apsusc.2008.06.127 ↗
7. [7] M. Supova, G. S. Martynkova and K. Barabaszova, Sci. Adv. Mater., 2011, 3, 1-25; https://doi.org/10.1166/sam.2011.113610.1166/sam.2011.1136 ↗
8. [8] F. Tan, M. Naciri, D. Dowling and M. Al-Rubeai, Biotechnol. Adv., 2012, 30, 352-362; https://doi.org/10.1016/j.biotechadv.2011.07.00810.1016/j.biotechadv.2011.07.008 ↗
9. [9] P. Wutticharoenmongkol, P. Pavasant and P. Supaphol, Biomacromolecules, 2007, 8, 2602- 2610; https://doi.org/10.1021/bm700451p10.1021/bm700451p ↗
10. [10] A. P. Marques and R. L. Reis, Mater. Sci. Eng. C, 2005, 25, 215-229; https://doi.org/10.1016/j.msec.2005.01.01310.1016/j.msec.2005.01.013 ↗
11. [11] L. Shor, S. Guceri, X. Wen, M. Gandhi and W. Sun, Biomaterials, 2007, 28, 5291-5297; https://doi.org/10.1016/j.biomaterials.2007.08.01810.1016/j.biomaterials.2007.08.018 ↗
12. [12] F. Causa, P. A. Netti, L. Ambrosio, G. Ciapetti, N. Baldini, S. Pagani, et al, J. Biomed. Mater. Res. A., 2006, 76, 151-162; https://doi.org/10.1002/jbm.a.3052810.1002/jbm.a.30528 ↗
13. [13] V. Guarino, F. Causa, P.A. Netti, G. Ciapetti, S. Pagani, D. Martini, N. Baldini and L. Ambrosio, J. Biomed. Mater. Res. B Appl. Biomater., 2008, 86, 548-557; https://doi.org/10.1002/jbm.b.3105510.1002/jbm.b.31055 ↗
14. [14] S. J. Heo, S. E. Kim, Y. T. Hyun, D. H. Kim, H. M. Lee, Y. M. Hwang, S. A. Park and J. W. Shin, Key Eng, Mat., 2007, 342-343, 369-372; https://doi.org/10.4028/www.scientific.net/KEM.342-343.36910.4028/www.scientific.net/KEM.342-343.369 ↗
15. [15] D. Verma, K. Katti and D. Katti, J. Biomed. Mater. Res. A., 2006, 78, 772-780; https://doi.org/10.1002/jbm.a.3077410.1002/jbm.a.30774 ↗
16. [16] P. Fabbri, F. Bondioli, M. Messori, C. Bartoli, D. Dinucci and F. Chiellini, J. Mater. Sci. Mater. Med., 2010, 21, 343-351; https://doi.org/10.1007/s10856-009-3839-510.1007/s10856-009-3839-5 ↗
17. [17] M. Catauro, M. G. Raucci, F. De Gaetano and A. Marotta, J. Mater. Sci., 2003, 38, 3097- 3102; https://doi.org/10.1023/A:102477311300110.1023/A:1024773113001 ↗
18. [18] M. Catauro, M. G. Raucci, F. de Gaetano, A. Buri, A. Marotta and L. Ambrosio, J. Mater. Sci. Mater. Med., 2004, 15, 991-995; https://doi.org/10.1023/B:JMSM.0000042684.13247.3810.1023/B:JMSM.0000042684.13247.38 ↗
19. [19] D. Hakimimehr, D. M. Liu and T. Troczynski, Biomaterials, 2005, 26, 7297-7303; https://doi.org/10.1016/j.biomaterials.2005.05.06510.1016/j.biomaterials.2005.05.065 ↗
20. [20] S. Z. C. Liou, S. Y. Chen and D. M. Liu, J. Mater. Sci.-Mater. M., 2004, 15, 1261-1266; https://doi.org/10.1007/s10856-004-5733-510.1007/s10856-004-5733-5 ↗
21. [21] Kumar, R. R., Thanigaivel, S., Priya, A. K., Karthick, A., Malla, C., Jayaraman, P., ... & Karami, A. M. (2022), Journal of Nanomaterials, 2022; https://doi.org/10.1155/2022/792927010.1155/2022/7929270 ↗
22. [22] F. Bakan, O. Lacin and H. Sarac, Powder Technol., 2013, 233, 295-302; https://doi.org/10.1016/j.powtec.2012.08.03010.1016/j.powtec.2012.08.030 ↗
23. [23] A. Y. Fadeev, R. Helmy and S. Marcinko, Langmuir, 2002, 18, 7521-7529; https://doi.org/10.1021/la020178u10.1021/la020178u ↗
24. [24] ISO IS: 'Polymer-based restorative materials', 4th edn, 2009, 4049 Dentistry.
25. [25] ISO IS: 'Determination of compressive properties', 2002, 04 Pastics.
26. [26] T. Kokubo and H. Takadama:, Biomaterials., 2006, 27, 2907-2915; https://doi.org/10.1016/j.biomaterials.2006.01.01710.1016/j.biomaterials.2006.01.017 ↗
27. [27] F. W. Liu, X. Z. Jiang, Q. H. Zhang and M. F. Zhu, Compos. Sci. Technol., 2014, 101, 86-93; https://doi.org/10.1016/j.compscitech.2014.07.00110.1016/j.compscitech.2014.07.001 ↗
28. [28] R. Kamalian, A. Yazdanpanah, F. Moztarzadeh, R. Ravarian, Z. Moztarzadeh, M. Tahmasbi and M. Mozafari, Ceram.-Silikaty, 2012, 56, 331-340.
29. [29] S. M. Abo-Naf, E. S. M. Khalil, E. S. M. El-Sayed, H. A. Zayed and R. A. Youness, Spectrochim. Acta A., 2015, 144, 88-98; https://doi.org/10.1016/j.saa.2015.02.07610.1016/j.saa.2015.02.076 ↗
30. [30] Thanigaivel, S., Bhullar, S. K., Chandrasekaran, N., Mukherjee, A., Thomas, J., & Ramalingam, M. (2018), Journal of Bionanoscience, 12(3), 417-421; https://doi.org/10.1166/jbns.2018.154210.1166/jbns.2018.1542 ↗
31. [31] Paramasivam, G., Palem, V. V., Sundaram, T., Sundaram, V., Kishore, S. C., & Bellucci, S. (2021), Nanomaterials, 11(12), 3228; https://doi.org/10.3390/nano1112322810.3390/nano11123228 ↗