journal article·2022-01Open access

Functionalization of surgical meshes with antibacterial hybrid Ag@crown nanoparticles

Baku State University, Chemical Department, Z.Khalilov 23, AZ 1148 Baku, Azerbaijan, U. A. Hasanova, A. R. Aliyev, Baku State University, Chemical Department, Z.Khalilov 23, AZ 1148 Baku, Azerbaijan, I. R. Hasanovaa, Baku State University, Chemical Department, Z.Khalilov 23, AZ 1148 Baku, Azerbaijan, E. M. Gasimov, Azerbaijan Medical University, Surgical Department Bakikhanov str. 23, AZ 1022, Baku, Azerbaijan, S. F. Hajiyeva, Baku State University, Chemical Department, Z.Khalilov 23, AZ 1148 Baku, Azerbaijan, A. A. Israyilovac, Department of Molecular biology and Biotechnology, Baku State University, Z.Khalilov 23, AZ 1148 Baku, Azerbaijan, Kh. G. Ganbarov, Laboratory of Microbiology and Virology, Baku State University, Z.Khalilov 23, AZ1148, Baku Azerbijan, Z. O. Gakhramanova, Azerbaijan State Oil and Industry University, Azadlıq Ave 16/21, AZ1010, Baku, Azerbaijan, P. F. Huseynova, Ganja State University, Chemical Department, Shah Ismayil Khetayi Ave, Ganja, Azerbaijan, N. R Amrahov, Department of Molecular biology and Biotechnology, Baku State University, Z.Khalilov 23, AZ 1148 Baku, Azerbaijan

Abstract

We report here on functionalization of surgical meshes (PVDF) with novel hybrid material, consisting of Ag@crown nanoparticles, embedded on CaCO3/PEG nanosheets. Nanosheets of PEG 4000 with average thickness of 25 nm enclosing CaCO3 nanoparticles with average sizes of 150 nm were applied for sustained release of Ag@crown nanoparticles that in turn serve as antibacterial agent. The characterization of obtained hybrid nanostructures was carried out by microscopic and spectroscopic methods. Microbiological tests confirmed the effectiveness of hybrid material, consisting of Ag@crown nanoparticles, embedded in CaCO3/PEG nanostructure, as an antibacterial coating for surgical meshes. This coating was applied to insure antibacterial properties of meshes against microorganism colonization, in order to significantly improve their action in typical applications.
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Research context

OpenAlex topics: Bone Tissue Engineering Materials · Nanoparticles: synthesis and applications · Polymer Nanocomposite Synthesis and Irradiation

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