DataVXAdvanced Functional MaterialsPaper
journal article·2021-10

Self‐Oxygenation of Tissues Orchestrates Full‐Thickness Vascularization of Living Implants (Adv. Funct. Mater. 42/2021)

Ali Farzin, Shabir Hassan, Liliana S. Moreira Teixeira, Melvin Gurian, João F. Crispim, Varun Manhas, Aurélie Carlier, Hojae Bae, Liesbet Geris, Iman Noshadi, Su Ryon Shin, Jeroen Leijten

Advanced Functional Materials· Volume 31· Issue 42
Publisher page
Source abstract

Abstract

Self-Oxygenating Tissues In article number 2100850, Jeroen Leijten and co-workers produce oxygen-generating micromaterials composed of polycaprolactone and calcium peroxide to engineer self-oxygenating living implants. Upon implantation, the self-oxygenation of tissues improve cell survival, enhance production of angiogenic factors, and orchestrate full-thickness vascularization. Self-oxygenation of tissues thus represents an effective and widely applicable strategy to enable the vascularization living implants.
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Research context

Biomaterials

OpenAlex topics: Electrospun Nanofibers in Biomedical Applications

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Affiliations

Division of Engineering in Medicine Department of Medicine Brigham and Women's Hospital Harvard Medical School Cambridge MA 02139 USA

Department of Tissue Engineering and Applied Cell Sciences School of Advanced Technologies in Medicine Tehran University of Medical Sciences Tehran Iran

Department of Developmental BioEngineering Technical Medical Centre University of Twente Enschede The Netherlands

Biomechanics Research Unit GIGA In Silico Medicine University of Liège Chemin des Chevreuils 1, B52/3 Liège 4000 Belgium

Laboratory for Cell Biology‐Inspired Tissue Engineering MERLN Institute University of Maastricht Maastricht The Netherlands

KU Convergence Science and Technology Institute Department of Stem Cell and Regenerative Biotechnology Konkuk University Seoul 05029 Republic of Korea

Department of Bioengineering University of California Riverside CA 92521 USA

References

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