journal article·2021-08Open access

Design and Engineering of Amyloid Aggregation‐Prone Fragments and Their Antimicrobial Conjugates with Multi‐Target Functionality (Adv. Funct. Mater. 32/2021)

Yanxian Zhang, Yijing Tang, Yonglan Liu, Dong Zhang, Jie Zheng

Advanced Functional Materials· Volume 31· Issue 32

Abstract

Amyloid Aggregation In article number 2102978, Jie Zheng and co-workers provide a new “kill two birds with one stone” model to not only reconcile with both the “amyloid cascade hypothesis” and “microbial infection hypothesis”, but also reveal the functional and structural correlations between antimicrobial peptides and amyloid proteins with their built-in bacterial killing and amyloid inhibition functions.
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Research context

OpenAlex topics: Alzheimer's disease research and treatments · Supramolecular Self-Assembly in Materials · Nanoplatforms for cancer theranostics

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Affiliations

Department of Chemical, Biomolecular, and Corrosion Engineering The University of Akron Akron OH USA

References

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