Tumor Microenvironment Remodeling: Biomimetic Nanomedicine Coupled with Neoadjuvant Chemotherapy to Suppress Breast Cancer Metastasis via Tumor Microenvironment Remodeling (Adv. Funct. Mater. 25/2021)
Source abstract
Abstract
In article number 2100262, Peisheng Xu and co-workers develop a homologous targeted cerium oxide nanoparticle system (T-CeNP) remodeling the tumor microenvironment through inhibiting cancer-associated fibroblast transdifferentiation and reprogramming it back to normal fibroblasts. T-CeNP coupled with doxorubicin reduces the size of the primary tumor and prevents post-surgery lung metastasis and liver metastasis of cancer in an orthotopic breast cancer model.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced Nanomaterials in Catalysis · Nanocluster Synthesis and Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Discovery and Biomedical Sciences College of Pharmacy University of South Carolina 715 Sumter Columbia SC 29208 USA
Department of Cell Biology and Anatomy School of Medicine University of South Carolina 6439 Garners Ferry Rod Columbia SC 29209 USA
Department of Neuroscience & Regenerative Medicine Medical College of Georgia at Augusta University 1120 15th St. Augusta GA 30912 USA
References
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