DataVXAdvanced Functional MaterialsPaper
journal article·2017-11Open access

Cancer Therapy: Photo‐Induced Charge‐Variable Conjugated Polyelectrolyte Brushes Encapsulating Upconversion Nanoparticles for Promoted siRNA Release and Collaborative Photodynamic Therapy under NIR Light Irradiation (Adv. Funct. Mater. 44/2017)

Hui Zhao, Wenbo Hu, Hengheng Ma, Rongcui Jiang, Yufu Tang, Yu Ji, Xiaomei Lu, Bing Hou, Weixing Deng, Wei Huang, Quli Fan

Advanced Functional Materials· Volume 27· Issue 44
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Source abstract

Abstract

In article number 1702592 Quli Fan and co-workers report a photo-induced charge-variable cationic conjugated polyelectrolyte brush encapsulating upconversion nanoparticles (UCNP@CCPEB) for siRNA release and collaborative photodynamic therapy under near-IR light irradiation. With good stability and excellent siRNA-loading capacity, UCNP@CCPEB exhibits good 1O2 production and facilitate siRNA release under 980 nm irradiation, enabling highly effective collaborative tumor therapy in vitro and in vivo.
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Research context

Nanomaterials

OpenAlex topics: RNA Interference and Gene Delivery · Nanoplatforms for cancer theranostics · Advanced biosensing and bioanalysis techniques

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Affiliations

Key Laboratory for Organic Electronics and Information Displays & Institute of Advanced Materials (IAM) Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM) Nanjing University of Posts & Telecommunications 9 Wenyuan Road Nanjing 210023 China

Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM) Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM) Nanjing Tech University (NanjingTech) 30 South Puzhu Road Nanjing 211816 China

References

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