journal article·2016-12Open access

Tissue Repair: Development of Therapeutic Small‐Molecule Fluorophore for Cell Transplantation (Adv. Funct. Mater. 46/2016)

Xin Wang, Zelin Chen, Shenglin Luo, Taotao Jin, Yu Wang, Fuqin Chen, Liao Wu, Xu Tan, Chunmeng Shi

Advanced Functional Materials· Volume 26· Issue 46

Abstract

The clinical application of cell-based therapy is severely hampered by restricted cell survival and poor understanding of cell fate after transplantation. C. Shi and co-workers describe a novel near-infrared mitochondria-targeting heptamethine dye (NIRCP-61) on page 8397, developed to simultaneously enable cell tracking and cytoprotection in cytotherapy. This small-molecule fluorophore maintains superior fluorescent imaging properties while inducing cytoprotective effects against oxidative stress to augment tissue repair and regeneration.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Tissue Engineering and Regenerative Medicine · Graphene and Nanomaterials Applications · 3D Printing in Biomedical Research

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Affiliations

Institute of Combined Injury State Key Laboratory of Trauma Burns and Combined Injury Chongqing Engineering Research Center for Nanomedicine College of Preventive Medicine Third Military Medical University 30th Gaotanyan street Chongqing 400038 China

School of Public Health Gui Zhou Medical University Guiyang 550004 China

References

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