journal article·2016-08

Decellularized Cartilage Microparticles: Dissociated and Reconstituted Cartilage Microparticles in Densified Collagen Induce Local hMSC Differentiation (Adv. Funct. Mater. 30/2016)

Tyler Novak, Benjamin Seelbinder, Celina M. Twitchell, Sherry L. Voytik‐Harbin, Corey P. Neu

Advanced Functional Materials· Volume 26· Issue 30
Publisher page

Abstract

On page 5427, C. P. Neu and co-workers report on successfully combining the benefits of native tissue biochemistry/structure with the tunability of reconstituted biomaterials for the formation of clinically relevant tissue composites. Native articular cartilage and reconstituted type I collagen form a moldable ‘cartilage clay’ that can be custom designed to meet the mechanical, biochemical, and geometric needs of a clinical implant; showing the capability to locally differentiate progenitor cells.
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Research context

OpenAlex topics: E-commerce and Technology Innovations · Osteoarthritis Treatment and Mechanisms · Electrospun Nanofibers in Biomedical Applications

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Affiliations

Weldon School of Biomedical Engineering Purdue University West Lafayette IN 47907 USA

Department of Mechanical Engineering University of Colorado Boulder Boulder CO 80304 USA

Department of Basic Medical Sciences Purdue University West Lafayette IN 47907 USA

References

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