journal article·2012-11-07

Cell Separation: Ethanol‐Dispersed Polymer Nanofibers as a Highly Selective Cell Isolation and Release Platform for CD4+ T Lymphocytes (Adv. Funct. Mater. 21/2012)

Seung‐Hyun Jun, Kwanghee Kim, Hyo Jin An, Byoung Chan Kim, Chung Hee Sonn, Miju Kim, Junsang Doh, Cassian Yee, Kyung‐Mi Lee, Jungbae Kim

Advanced Functional Materials· Volume 22· Issue 21
Publisher page

Abstract

Electrospun and alcohol-dispersed polystyrene-poly(styreneco-maleic anhydride) (PS-PSMA) nanofibers, which allow for facile conjugation of antibodies, are used as an innovative cell isolation/enrichment and support/release platform. As reported by Kyung-Mi Lee, Jungbae Kim, and co-workers on page 4448, this work opens up the potential for an innovative immune cell therapy in which specific immune cells are isolated by antibody-conjugated nanofibers and are directly delivered to the target sites under the controlled and sustained release of immune cells via in vivo activation.
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Research context

OpenAlex topics: Electrospun Nanofibers in Biomedical Applications

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