journal article·2020-04Open access

Islet Transplantation: A Collagen Based Cryogel Bioscaffold that Generates Oxygen for Islet Transplantation (Adv. Funct. Mater. 15/2020)

Mehdi Razavi, Rosita Primavera, Bhavesh D. Kevadiya, Jing Wang, Peter Buchwald, Avnesh S. Thakor

Advanced Functional Materials· Volume 30· Issue 15

Abstract

In article number 1902463, Avnesh S. Thakor and co-workers design a macroporous collagen-based cryogel bioscaffold that can accommodate transplanted pancreatic islets. Calcium peroxide, which generates a steady supply of oxygen, is then incorporated into the matrix of this bioscaffold. This clinically translatable platform improves the function and viability of transplanted islets until they can establish a new blood supply, and hence their own source of oxygen, following transplantation.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Pancreatic function and diabetes · Tissue Engineering and Regenerative Medicine

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Affiliations

Interventional Regenerative Medicine and Imaging Laboratory Stanford University School of Medicine Department of Radiology Palo Alto CA 94304 USA

Biionix (Bionic Materials, Implants and Interfaces) Cluster Department of Internal Medicine College of Medicine University of Central Florida Orlando FL 32827 USA

Diabetes Research Institute Miller School of Medicine University of Miami Miami FL 33136 USA

References

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