journal article·2016-02

Nanostructures: Enhanced Differentiation of Human Embryonic Stem Cells Toward Definitive Endoderm on Ultrahigh Aspect Ratio Nanopillars (Adv. Funct. Mater. 6/2016)

Camilla Holzmann Rasmussen, Paul M. Reynolds, Dorthe Roenn Petersen, Mattias Hansson, Robert M. McMeeking, Martin Dufva, Nikolaj Gadegaard

Advanced Functional Materials· Volume 26· Issue 6
Publisher page

Abstract

N. Gadegaard and co-workers report on page 815 a nanofabricated thermoplastic substrate with ultra-high aspect ratio nanopillars. This substrate, formed via injection molding, is used to enhance the differentiation of human embryonic stem cells. The nanostructured surface results in a softer substrate, which mimics the natural extracellular environment.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: 3D Printing in Biomedical Research · Graphene and Nanomaterials Applications · Bone Tissue Engineering Materials

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Affiliations

Novo Nordisk A/S Novo Nordisk Park 2760 Maaloev Denmark

DTU Nanotech Technical University of Denmark (DTU) 2800 Kgs. Lyngby Denmark

Division of Biomedical Engineering School of Engineering University of Glasgow Glasgow G12 8LT UK

Department of Materials University of California Santa Barbara CA 93106 USA

School of Engineering University of Aberdeen King's College Aberdeen AB24 3UE UK

Department of Mechanical Engineering University of California Santa Barbara CA 93106 USA

References

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