Drug Delivery: Fabrication of Nanofiber Microarchitectures Localized within Hydrogel Microparticles and Their Application to Protein Delivery and Cell Encapsulation (Adv. Funct. Mater. 5/2013)

On page 591, Won-Gun Koh and co-workers report a simple method to generate well-defined microscopic architectures of electrospun nanofibers and describe their potential applications in biomedical fields. A combination of electrospinning and hydrogel patterning generates microarchitectured nanofibers that are localized within various shapes of hydrogel microparticles. Resultant nanofiber-entrapped hydrogels can be used for sustained release of protein and cell encapsulation