Gene Delivery: Nano‐Self‐Assembly of Nucleic Acids Capable of Transfection without a Gene Carrier (Adv. Funct. Mater. 34/2015)
Source abstract
Abstract
On page 5445, Y.-W. Won, D. A. Bull, and co-workers show that Zn2+ is able to assemble nucleic acids into a nanocluster that is capable of spontaneous internalization into cells. Zn2+ shows superior gene transfection efficiency among the three divalent metal ions tested. Various endocytosis mechanisms are involved in the cellular uptake of the Zn/DNA cluster.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: RNA Interference and Gene Delivery · Advanced biosensing and bioanalysis techniques
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Division of Cardiothoracic Surgery Department of Surgery University of Utah School of Medicine Salt Lake City UT 84132 USA
Department of Pharmaceutics and Pharmaceutical Chemistry University of Utah Salt Lake City UT 84112 USA
References
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