DataVXAdvanced Functional MaterialsPaper
journal article·2022-10

Hesperetin Nanoparticle Targeting Neutrophils for Enhanced TBI Therapy (Adv. Funct. Mater. 43/2022)

Kai Yao, Qingchun Mu, Yufei Zhang, Qian Cheng, Xiaozhi Cheng, Xiaojing Liu, Chunmei Luo, Chumei Li, Shuxia Cai, Zhicheng Luo, Xiulong Zhu, Xiangtong Zhang, Liao Cui, Chunming Huang, Longguang Tang

Advanced Functional Materials· Volume 32· Issue 43
Publisher page
Source abstract

Abstract

Hesperetin Nanoparticles In article number 2205787, Xiangtong Zhang, Liao Cui, Chunming Huang, Longguang Tang, and co-workers design a hesperetin nanoparticle that targets neutrophils, T-Hes, catalyzed by myeloperoxidase secreted by neutrophils, which can effectively identify inflammatory neutrophils and quickly gather in the injured area after traumatic brain injury. The sustained release of hesperetin by T-Hes shows great advantages in anti-inflammatory treatment, reducing brain edema and improving neurological function.
Source: openalex_inverted_index · Quality: baseline

Research context

NanomaterialsCatalysis & surfaces

OpenAlex topics: Inflammation biomarkers and pathways · Neurological Disorders and Treatments · Nanoplatforms for cancer theranostics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Neurosurgery First Affiliated Hospital of Harbin Medical University Harbin 150001 China

The People's Hospital of Gaozhou Maoming 525200 China

College of Pharmacy Guilin Medical University Guilin 541199 China

Guangdong Provincial Key Laboratory of Research and Development of Natural Drugs School of Pharmacy Guangdong Medical University Dongguan 523808 China

International Institutes of Medicine The Fourth Affiliated Hospital Zhejiang University School of Medicine Yiwu 322000 China

References

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