journal article·2021-09Open access

Immunoregulation of Macrophages by Controlling Winding and Unwinding of Nanohelical Ligands (Adv. Funct. Mater. 37/2021)

Gunhyu Bae, Yoo Sang Jeon, Min Jun Ko, Yuri Kim, Seong‐Beom Han, Ramar Thangam, Wonsik Kim, Hee Joon Jung, Sungkyu Lee, Hyojun Choi, Sunhong Min, Hyunsik Hong, Sangwoo Park, Seong Yeol Kim, Kapil D. Patel, Na Li, Jeong Eun Shin, Bum Chul Park, Hyeon Su Park, Jun Hwan Moon, Yu Jin Kim, Uday Kumar Sukumar, Jae‐Jun Song, Soo Young Kim, Seung‐Ho Yu, Yun Chan Kang, Steve Park, Seung Min Han, Dong‐Hwee Kim, Ki‐Bum Lee, Qiang Wei, Liming Bian, Ramasamy Paulmurugan, Young Keun Kim, Heemin Kang

Advanced Functional Materials· Volume 31· Issue 37

Abstract

Macrophage Polarization In article number 2103409, Young Keun Kim, Heemin Kang, and co-workers present an adhesive nanohelical nanostructure that is partially affixed to the surface, which can be actively manipulated to wind in any direction. This active winding modulates integrin recruitment onto the adhesive nanostructure at a single cell level to mediate an assembly of adhesion structures that stimulates regenerative immunomodulation.
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Research context

OpenAlex topics: Tissue Engineering and Regenerative Medicine · Graphene and Nanomaterials Applications

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Affiliations

Department of Materials Science and Engineering Korea University Seoul 02841 Republic of Korea

KU‐KIST Graduate School of Converging Science and Technology Korea University Seoul 02841 Republic of Korea

Department of Materials Science and Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon 34141 Republic of Korea

Department of Materials Science and Engineering Northwestern University Evanston IL 60208 USA

International Institute for Nanotechnology Evanston IL 60208 USA

NUANCE Center Northwestern University Evanston IL 60208 USA

Institute for High Technology Materials and Devices Korea University Seoul 02841 Republic of Korea

Department of Otorhinolaryngology‐Head and Neck Surgery Korea University College of Medicine Seoul 08308 Republic of Korea

Department of Radiology, Molecular Imaging Program at Stanford Stanford University School of Medicine Stanford University Palo Alto CA 94304 USA

Department of Chemical and Biological Engineering Korea University Seoul 02841 Republic of Korea

Department of Chemistry and Chemical Biology Rutgers University Piscataway NJ 08854 USA

College of Polymer Science and Engineering State Key Laboratory of Polymer Materials and Engineering Sichuan University Chengdu 610065 China

Department of Biomedical Engineering The Chinese University of Hong Kong Hong Kong 999077 China

Department of Radiology Canary Center at Stanford for Cancer Early Detection Stanford University School of Medicine Stanford University Palo Alto CA 94304 USA

Department of Biomicrosystem Technology Korea University Seoul 02841 Republic of Korea

References

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