DataVXAdvanced Functional MaterialsPaper
journal article·2019-04Open access

Recyclable Cytokines: Recyclable Cytokines on Short and Injectable Polylactic Acid Fibers for Enhancing T‐Cell Function (Adv. Funct. Mater. 14/2019)

Hyun Mu Shin, Youngjun Ju, Gwanghun Kim, Jae Won Lee, Myung Won Seo, Ji Hyun Sim, Jusang Yang, Sora Noh, Jungbae Kim, Hang‐Rae Kim

Advanced Functional Materials· Volume 29· Issue 14
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Source abstract

Abstract

In article number 1808361, Jungbae Kim, Hang-Rae Kim, and co-workers inject cytokine-immobilized short polylactic acid (PLA) fibers (Cyto-sPLA) near a tumor to reinvigorate nonfunctional T cells. The administration of Cyto-sPLA fibers kills tumor cells and ultimately effectively inhibits tumor growth. Injectable Cyto-sPLA fibers have great potential for the development of anticancer therapeutics.
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Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Tissue Engineering and Regenerative Medicine · Graphene and Nanomaterials Applications

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Affiliations

Department of Anatomy and Cell Biology Seoul National University College of Medicine Seoul 03080 Republic of Korea

Department of Biomedical Sciences Seoul National University College of Medicine Seoul 03080 Republic of Korea

BK21Plus Biomedical Science Project Seoul National University College of Medicine Seoul 03080 Republic of Korea

Medical Research Institute Seoul National University College of Medicine Seoul 03080 Republic of Korea

Department of Chemical and Biological Engineering Korea University Seoul 02841 Republic of Korea

References

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