Novel Bilayer Microarray Patch‐Assisted Long‐Acting Micro‐Depot Cabotegravir Intradermal Delivery for HIV Pre‐Exposure Prophylaxis (Adv. Funct. Mater. 9/2022)
Source abstract
Abstract
HIV Pre-Exposure Prophylaxis In article number 2106999, Ryan F. Donnelly and co-workers develop a novel bilayer polymeric microarray patch (MAP) with highly drug-loaded tips for intradermal long-acting delivery of cabotegravir for HIV pre-exposure prophylaxis. This MAP delivers substantial amounts of the drug into the skin as implanted micro-depots, which are shown to maintain human therapeutic levels in rats for 1 month after a single application.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Advancements in Transdermal Drug Delivery · Advanced Drug Delivery Systems · HIV Research and Treatment
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
School of Pharmacy Medical Biology Centre Queen's University Belfast 97 Lisburn Road Belfast Northern Ireland BT9 7BL UK
Faculty of Pharmacy Aleppo University Aleppo Syria
PATH 2201 Westlake Avenue Seattle WA 98121 USA
References
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