journal article·2020-07Open access

Bone Composites: Citrate‐Based Tannin‐Bridged Bone Composites for Lumbar Fusion (Adv. Funct. Mater. 27/2020)

Jinshan Guo, Xinggui Tian, Denghui Xie, Kevin Rahn, Ethan Gerhard, Michelle Laurel Kuzma, Dongfang Zhou, Cheng Dong, Xiaochun Bai, Zhihui Lu, Jian Yang

Advanced Functional Materials· Volume 30· Issue 27

Abstract

In article number 2002438, Xiaochun Bai, Zhihui Lu, Jian Yang, and co-workers, strategically use multi-functional tannin to bridge inorganic and organic phases of composite materials in orthopedic biomaterial design. By adhering to the inorganic phase, hydroxyapatite, and chemically reacting with the organic phase, citrate-based polymers using tannin, the citrate-based tannin-bridged bone composites present greatly improved compression strengths, significant antimicrobial properties, and enhanced biomineralization and osteoconductivity for in vivo lumbar fusion.
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Research context

OpenAlex topics: Spine and Intervertebral Disc Pathology · Bone Tissue Engineering Materials

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Affiliations

Department of Histology and Embryology School of Basic Medical Sciences Department of Orthopedic Surgery The Third Affiliated Hospital of Southern Medical University Southern Medical University Guangzhou 510515 P. R. China

Academy of Orthopedics of Guangdong Province Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases Guangzhou 510630 P. R. China

Department of Biomedical Engineering Materials Research Institute The Huck Institutes of The Life Sciences The Pennsylvania State University University Park PA 16802 USA

Department of Spine Surgery The Affiliated Hospital of Southwest Medical University Luzhou Sichuan 646000 P. R. China

School of Pharmaceutical Sciences Southern Medical University Guangzhou 510515 P. R. China

Department of Biology School of Basic Medical Sciences Southern Medical University Guangzhou 510515 P. R. China

References

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