journal article·2018-09Open access

Cancer Theranostics: Myeloid‐Derived Suppressor Cell Membrane‐Coated Magnetic Nanoparticles for Cancer Theranostics by Inducing Macrophage Polarization and Synergizing Immunogenic Cell Death (Adv. Funct. Mater. 37/2018)

Guang‐Tao Yu, Lang Rao, Hao Wu, Lei‐Lei Yang, Lin‐Lin Bu, Wei‐Wei Deng, Lei Wu, Xiaolin Nan, Wen‐Feng Zhang, Xing‐Zhong Zhao, Wei Liu, Zhi‐Jun Sun

Advanced Functional Materials· Volume 28· Issue 37

Abstract

In article number 1801389, Wei Liu, Zhi-Jun Sun, and co-workers report a biomimetic nanoparticle based on a myeloid-derived suppressor cell membrane-coated Fe3O4 magnetic nanoparticle (MDSC@MNP) for cancer theranostics. This nanoparticle demonstrates its superior performance in immune evasion, active tumor targeting, magnetic resonance imaging (MRI), macrophage polarization, and photothermal therapy (PTT)-induced tumor killing. The work provides a promising ingenious biomimetic nanoparticle for cancer treatment.
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Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced Nanomaterials in Catalysis · Nanoparticle-Based Drug Delivery

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Affiliations

The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education and Department of Oral Maxillofacial‐Head Neck Oncology School and Hospital of Stomatology Wuhan University Wuhan Hubei 430079 China

Key Laboratory of Artificial Micro‐ and Nano‐Structure of Ministry of Education School of Physics and Technology Wuhan University Wuhan Hubei 430072 China

Department of Biomedical Engineering, Center for Spatial Systems Biomedicine, and Center for Cancer Early Detection Advanced Research Knight Cancer Institute Oregon Health and Science University Portland OR 97201 USA

References

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