DataVXAdvanced Functional MaterialsPaper
journal article·2024-08Open access

Photosensitive Nanoprobes for Rapid High Purity Isolation and Size‐Specific Enrichment of Synthetic and Extracellular Vesicle Subpopulations (Adv. Funct. Mater. 34/2024)

Jonathan S. Weerakkody, Tiffany Tseng, Mackenzie Topper, Sikha Thoduvayil, Abhijith Radhakrishnan, Frederic Pincet, Themis R. Kyriakides, Roshan W. Gunasekara, Sathish Ramakrishnan

Advanced Functional Materials· Volume 34· Issue 34
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Source abstract

Abstract

Photosensitive Nanoprobes In article number 2400390, Roshan W. Gunasekara, Sathish Ramakrishnan, and co-workers develop photosensitive lipid nanoprobes to isolate high-purity native extracellular vesicles while maintaining their nativity and functionality. Utilizing hydrophobic interactions and photochemistry, these probes separate vesicles into size-specific subpopulations. This unique property aids in understanding vesicle biogenesis, as size variability may indicate diverse cellular origins and functions, and facilitates the engineering of uniform vesicle populations.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Supramolecular Self-Assembly in Materials · Nanocluster Synthesis and Applications · Laser-Ablation Synthesis of Nanoparticles

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Affiliations

Yale Nanobiology Institute West Haven CT 06516 USA

Department of Pathology Yale University School of Medicine New Haven CT 06510 USA

Department of Cell Biology Yale University School of Medicine New Haven CT 06510 USA

Laboratoire de Physique de l'Ecole Normale Superieure Ecole Normale Superieure (ENS) Universite Paris Sciences et Lettres (PSL) CNRS Sorbonne Universite Universite Paris‐Cite Paris 75005 France

Department of Neurology Yale University School of Medicine New Haven CT 06510 USA

References

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