Collagen cross-linking and antibacterial enhancement in dental adhesives via lignin and lignin-capped silver nanoparticles fillers
Source abstract
Abstract
The longevity of dental restorations is highly dependent on the durability of the resin-dentin interface, where collagen degradation and bacterial infiltration remain key challenges. Lignin, a natural and sustainable polymer, offers antioxidant, cross-linking, and antimicrobial potential, and its combination with silver nanoparticles (AgNPs) could further enhance antibacterial efficacy. This study aimed to investigate the use of lignin and lignin-capped AgNPs (lignin/AgNPs) as bio-based fillers in dental adhesives to improve collagen stability and antibacterial performance. Incorporating 0.5 wt% lignin and 0.5 wt% lignin/AgNPs into dental adhesives significantly improved bond strength, increasing from 15.36 MPa to 22.87 MPa and 27.54 MPa, respectively. FTIR analysis confirmed improved collagen cross-linking. While lignin alone provided limited antibacterial effects, lignin/AgNPs achieved strong activity against Streptococcus mutans. Importantly, both adhesives maintained bond strength after 6-month aging and exhibited no cytotoxicity at clinically relevant concentrations. These findings support their application in the development of advanced dental materials.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Lignin and Wood Chemistry · Dental materials and restorations · Enzyme-mediated dye degradation
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Chemistry, Faculty of Science, Kasetsart University
Center of Excellence for Innovation in Chemistry, Faculty of Science, Kasetsart University
Research Center, Faculty of Dentistry, Mahidol University
Department of Zoology, Faculty of Science, Kasetsart University
Department of Microbiology, Faculty of Science, Kasetsart University
Biodiversity Center Kasetsart University (BDCKU)
References (33)
Show source-provided references
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