Novel self-etching and antibacterial orthodontic adhesive containing dimethylaminohexadecyl methacrylate to inhibit enamel demineralization
Source abstract
Abstract
Enamel demineralization is one of the most undesired side effects of fixed orthodontic treatment, which will lead to white spot lesions (WSLs) on tooth surfaces. The development of WSLs is due to prolonged accumulation of bacterial plaque and associated acid production. Self-etching adhesives have been used in orthodontic treatments with several advantages over the more traditional acid-etch method. However, current self-etching adhesives in orthodontic treatments have no antibacterial activity. The objectives of this study were to develop a self-etching and antibacterial orthodontic adhesive, and to investigate its enamel bond strength and antibacterial properties. A novel quaternary ammonium monomer dimethylaminohexadecyl methacrylate (DMAHDM) was incorporated into a commercial self-etching adhesive (Adper Easy One, 3M). It showed that the 5% DMAHDM appeared to be optimal in obtaining the strongest antibacterial function without compromising the enamel bond strength both at 15 min and after 30 days of immersion plus thermal cycling.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Dental materials and restorations · Dental Research and COVID-19 · Oral microbiology and periodontitis research
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Orthodontics, School of Stomatology, Capital Medical University
Department of Orthodontics, The First Affiliated Hospital of Dalian Medical University
Biomaterials & Tissue Engineering Division, Department of Endodontics, Prosthodontics and Operative Dentistry, University of Maryland Dental School
Center for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine
Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine
Department of Mechanical Engineering, University of Maryland
References (44)
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