Cariotester, a new device for assessment of dentin lesion remineralization in vitro
Source abstract
Abstract
This study aimed to evaluate the potential of a new device (Cariotester) for monitoring of incipient carious lesion remineralization in root dentin by topical fluoride in vitro. Demineralized bovine dentin specimens were treated by fluoride solutions (APF or neutral NaF) and remineralized for 4 weeks. Cariotester was used to measure penetration depth (CTR depth) of the indenter into the de- and remineralized specimen surface. The specimens were assessed by transverse microradiography (TMR) to determine lesion parameters (depth: LD, mineral loss: ΔZ). Pearson's correlation analysis showed an overall significant relationship between CTR depth and both TMR parameters. CTR depth appeared to distinguish the positive effect that topical fluoride application had on the remineralization of the outer zone of dentin lesions. Cariotester had the potential to serve as a quantitative tool for monitoring of incipient carious lesion remineralization in root dentin.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Dental materials and restorations · Dental Erosion and Treatment · Dental Radiography and Imaging
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (27)
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1. 1) Walls AW, Meurman JH. Approaches to caries prevention and therapy in the elderly. Adv Dent Res 2012; 24: 36-40.10.1177/0022034512453590 ↗
2. 2) Yoshihara A, Hanada N, Miyazaki H. Association between serum albumin and root caries in community-dwelling older adults. J Dent Res 2003; 82: 218-222.10.1177/154405910308200313 ↗
3. 3) Yoshihara A, Takano N, Hirotomi T, Ogawa H, Hanada N, Miyazaki H. Longitudinal relationship between root caries and serum albumin. J Dent Res 2007; 86: 1115-1119.10.1177/154405910708601118 ↗
4. 4) Kaneko M, Yoshihara A, Miyazaki H. Relationship between root caries and cardiac dysrhythmia. Gerodontology 2011; 28: 289-295.10.1111/j.1741-2358.2010.00367.x ↗
5. 5) Baysan A, Lynch E, Ellwood R, Davies R, Petersson L,Borsboom P. Reversal of primary root caries using dentifrices containing 5,000 and 1,100 ppm fluoride. Caries Res 2001; 35: 41-46.10.1159/000047429 ↗
6. 6) Marinho VC, Higgins JP, Logan S, Sheiham A. Fluoride varnishes for preventing dental caries in children and adolescents. Cochrane Database Syst Rev 2002; (3): CD002279.10.1002/14651858.CD002279 ↗
7. 7) Lynch E, Beighton D. A comparison of primary root caries lesions classified according to colour. Caries Res 1994; 28: 233-239.10.1159/000261971 ↗
8. 8) Momoi Y, Hayashi M, Fujitani M, Fukushima M, Imazato S, Kubo S, Nikaido T, Shimizu A, Unemori M, Yamaki C. Clinical guidelines for treating caries in adults following a minimal intervention policy-evidence and consensus based report. J Dent 2012; 40: 95-105.10.1016/j.jdent.2011.10.011 ↗
9. 9) Longbottom C, Huysmans MC. Electrical measurements for use in caries clinical trials. J Dent Res 2004; 83: 76-79.10.1177/154405910408301s15 ↗
10. 10) Baysan A, Prinz JF, Lynch E. Clinical criteria used to detect primary root caries with electrical and mechanical measurements in vitro. Am J Dent 2004; 17: 94-98.
11. 11) Zhang W, McGrath C, Lo EC. A comparison of root caries diagnosis based on visual-tactile criteria and DIAGNOdent in vivo. J Dent 2009; 37: 509-513.10.1016/j.jdent.2009.03.009 ↗
12. 12) Natsume Y, Nakashima S, Sadr A, Shimada Y, Tagami J, Sumi Y. Estimation of lesion progress in artificial root caries by swept source optical coherence tomography in comparison to transverse microradiography. J Biomed Opt 2011; 16: 071408.10.1117/1.3600448 ↗
13. 13) Shimizu A. Newly developed hardness testing system for carious dentin “CARIOTESTER” and its applications. J J Dent Mater and Devices 2011; 30: 29-32.
14. 14) Kusakabe S, Fujii K, Shimode A, Shimizu A, Hotta M. Trial for student education on hardness testing system for carious dentin. Abstract 136th Meeting of Jpn J Conserv Dent 2012: 104.
15. 15) Nakashima S, Nikaido T, Shimizu A, Tagami J. In vitro study on CarioTester as a diagnostic tool for root caries progression in comparison with TMR. Abstract 136th Meeting of Jpn J Conserv Dent 2012: 114.
16. 16) Fusayama T, Okuse K, Hosoda H. Relationship between hardness, discoloration, and microbial invasion in carious dentin. J Dent Res 1966; 45: 1033-1046.10.1177/00220345660450040401 ↗
17. 17) Featherstone JD, ten Cate JM, Shariati M, Arends J. Comparison of artificial caries-like lesions by quantitative microradiography and microhardness profiles. Caries Res 1983; 17: 385-391.10.1159/000260692 ↗
18. 18) Pugach MK, Strother J, Darling CL, Fried D, Gansky SA, Marshall SJ, Marshall GW. Dentin caries zones: mineral, structure, and properties. J Dent Res 2009; 88: 71-76.10.1177/0022034508327552 ↗
19. 19) Fure S, Lingström P. Evaluation of different fluoride treatments of initial root carious lesions in vivo. Oral Health Prev Dent 2009; 7: 147-154.
20. 20) Lee YE, Baek HJ, Choi YH, Jeong SH, Park YD, Song KB. Comparison of remineralization effect of three topical fluoride regimens on enamel initial carious lesions. J Dent 2010; 38: 166-171.10.1016/j.jdent.2009.10.002 ↗
21. 21) Diamanti I, Koletsi-Kounari H, Mamai-Homata E, Vougiouklakis G. Effect of fluoride and of calcium sodium phosphosilicate toothpastes on pre-softened dentin demineralization and remineralization in vitro. J Dent 2010; 38: 671-677.10.1016/j.jdent.2010.05.010 ↗
22. 22) Fujikawa H, Matsuyama K, Uchiyama A, Nakashima S, Ujiie T. Influence of salivary macromolecules and fluoride on enamel lesion remineralization in vitro. Caries Res 2008; 42: 37-45.10.1159/000111748 ↗
23. 23) Higham SM, Pretty IA, Edgar WM, Smith PW. The use of in situ models and QLF for the study of coronal caries. J Dent 2005; 33: 235-241.10.1016/j.jdent.2004.10.016 ↗
24. 24) Gmür R, Giertsen E, van der Veen MH, de Josselin de Jong E, ten Cate JM, Guggenheim B. In vitro quantitative light-induced fluorescence to measure changes in enamel mineralization. Clin Oral Investig 2006; 10: 187-195.10.1007/s00784-006-0058-z ↗
25. 25) Bobji MS, Biswas SK. Deconvolution of hardness from data obtained from nanoindentation of rough surfaces. J Mater Res 1999; 14: 2259-2268.10.1557/JMR.1999.0302 ↗
26. 26) Ogaard B. CaF2 formation: cariostatic properties and factors of enhancing the effect. Caries Res 2001; 35: 40-44.10.1159/000049109 ↗
27. 27) Tschoppe P, Meyer-Lueckel H. Mineral distribution of artificial dentinal caries lesions after treatment with fluoride agents in combination with saliva substitutes. Arch Oral Biol 2011; 56: 775-784.10.1016/j.archoralbio.2011.01.002 ↗