Fatigue testing of biomaterials and their interfaces

Objective The objective of this article is to describe the importance of fatigue to the success of restorative dentistry, with emphasis on the methods for evaluating the fatigue properties of materials in this field, and the durability of their bonded interfaces. Methods The stress-life fatigue and fatigue crack growth approaches for evaluating the fatigue resistance of dental biomaterials are introduced. Emphasis is placed on in vitro studies of the hard tissue foundation, restorative materials and their bonded interfaces. The concept of durability is then discussed, including the effects of conventional "mechanical" fatigue combined with pervasive threats of the oral environment, including variations in pH and the activation of endogenous dentin proteases. Results There is growing evidence that fatigue is a principal contributor to the failure of restorations and that measures of static strength, used in qualifying new materials and practices, are not reflective of the fatigue performance. Results of selected studies show that the fundamental steps involved in the placement of restorations, including the cutting of preparations and etching, cause a significant reduction to the fatigue strength of the hard tissue foundation. In regards to the bonded interface, results of studies focused on fatigue resistance highlight the importance of the hybridization of resin tags, and that a reduction in integrity of the dentin collagen is detrimental to the durability of dentin bonds. Significance Fatigue should be a central concern in the development of new dental materials and in assessing the success of restorative practices. A greater recognition of contributions from fatigue to restoration failures, and the development of approaches with closer connection to in vivo conditions, will be essential for extending the definition of lifelong oral health.