The Rise of Scanning Electrochemical Cell Microscopy: From Correlative Insights to an Automated Platform

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2. Operando scanning electrochemical probe microscopy during electrocatalysis10.1021/acs.chemrev.2c00766 ↗

3. Scanning electrochemical microscopy: an evolving toolbox for revealing the chemistry within electrochemical processes10.1021/acs.analchem.4c06996 ↗

4. A look inside a flexible open-source scanning electrochemical probe microscope10.1021/acselectrochem.5c00354 ↗

5. Scanning electrochemical microscopy10.1021/ac00194a735 ↗

6. Scanning electrochemical microscopy. Introduction and principles10.1021/ac00177a011 ↗

7. Localized high resolution electrochemistry and multifunctional imaging: scanning electrochemical cell microscopy10.1021/ac102191u ↗

8. Five years of scanning electrochemical cell microscopy (SECCM): new insights and innovations10.1039/D4NR00859F ↗

9. A tutorial for scanning electrochemical cell microscopy (SECCM) measurements: step-by-step instructions, visual resources, and guidance for first experiments10.1021/acsmeasuresciau.4c00091 ↗

10. Dynamics of solid-electrolyte interphase formation on silicon electrodes revealed by combinatorial electrochemical screening10.1002/anie.202207184 ↗

11. Scanning electrochemical cell microscopy for sub-micrometer mass spectrometric studies of electrochemical reactions10.1021/acselectrochem.5c00095 ↗

12. Spatially resolved optical spectroscopic measurements with simultaneous photoelectrochemical mapping using scanning electrochemical probe microscopy10.1021/acs.jpclett.3c00603 ↗

13. Pseudo-single-crystal electrochemistry on polycrystalline electrodes: visualizing activity at grains and grain boundaries on platinum for the Fe2+/Fe3+ redox reaction10.1021/ja310632k ↗

14. Improved spatial resolution for spot sampling in thermal desorption atomic force microscopy – mass spectrometry via rapid heating functions10.1039/C6NR09675A ↗

15. Electrochemical push–pull scanner with mass spectrometry detection10.1021/ac300999v ↗

16. Colocalized Raman spectroscopy–scanning electrochemical microscopy investigation of redox flow battery dialkoxybenzene redoxmer degradation pathways10.1016/j.electacta.2023.142123 ↗

17. Interrogating charge storage on redox active colloids via combined Raman spectroscopy and scanning electrochemical microscopy10.1021/acs.langmuir.7b01121 ↗

18. Screening surface structure-electrochemical activity relationships of copper electrodes under CO2 electroreduction conditions10.1021/acscatal.2c01650 ↗

19. High resolution mapping of oxygen reduction reaction kinetics at polycrystalline platinum electrodes10.1039/C4CP01511H ↗

20. Selective increase in CO2 electroreduction activity at grain-boundary surface terminations10.1126/science.aao3691 ↗

21. Electrochemical maps and movies of the hydrogen evolution reaction on natural crystals of molybdenite (MoS2): basal vs. edge plane activity10.1039/C7SC02545A ↗

22. Nanoscale electrochemistry of sp2 carbon materials: from graphite and graphene to carbon nanotubes10.1021/acs.accounts.6b00301 ↗

23. Interfacial chemistry effects in the electrochemical performance of silicon electrodes under lithium-ion battery conditions10.1002/smll.202303442 ↗

24. Surface nanostructure effects on dopamine adsorption and electrochemistry on glassy carbon electrodes10.1021/acs.jpcc.2c02801 ↗

25. Depth-resolved probing of native solid electrolyte interphase formation and dynamics in Li metal batteries by cryogenic X-ray photoelectron spectroscopy10.1021/jacs.5c09519 ↗

26. Electrochemical formation of bis(fluorosulfonyl)imide-derived solid-electrolyte interphase at Li-metal potential10.1038/s41557-024-01689-5 ↗

27. Surface structure and grain boundary effects on the oxygen evolution reaction at gold electrodes10.1021/acselectrochem.5c00224 ↗

28. Intrinsic electrocatalytic activity of platinum grain boundaries: correcting measurement artefacts in scanning electrochemical cell microscopy (SECCM)10.1039/D5SC03829D ↗

29. Step edge defects have nanoscale impact on the electronic structure in semiconducting transition metal dichalcogenide electrocatalysts10.1021/jacs.4c17263 ↗

30. High-throughput combinatorial analysis of the spatiotemporal dynamics of nanoscale lithium metal plating10.1021/acsnano.4c05001 ↗

31. Operando electrochemical and optical characterization of the meniscus of scanning electrochemical cell microscopy (SECCM) probes10.1021/acselectrochem.4c00029 ↗

32. Quad-barrel multifunctional electrochemical and ion conductance probe for voltammetric analysis and imaging10.1021/acs.analchem.5b00379 ↗

33. Integration of scanning electrochemical microscopy and scanning electrochemical cell microscopy in a bifunctional nanopipette toward simultaneous mapping of activity and selectivity in electrocatalysis10.1021/acs.analchem.4c00149 ↗

34. Simultaneous mapping of electrocatalytic activity and selectivity via hybrid scanning electrochemical probe microscopy10.1021/acs.nanolett.4c01280 ↗

35. Time-resolved product observation for CO2 electroreduction using synchronised electrochemistry-mass spectrometry with soft ionisation (sEC-MS-SI)

36. Real-time in situ monitoring of CO2 electroreduction in the liquid and gas phases by coupled mass spectrometry and localized electrochemistry10.1021/acscatal.2c00609 ↗

37. Real-time probing of electrochemical intermediates: mechanistic insights via ambient mass spectrometry10.1021/acs.analchem.5c03426 ↗

38. In conversation: scanning electrochemical cell microscopy (SECCM) meets mass spectrometry10.1021/acselectrochem.5c00222 ↗

39. Scanning electrochemical microscopy. 47. Imaging electrocatalytic activity for oxygen reduction in an acidic medium by the tip generation-substrate collection mode10.1021/ac0340354 ↗

40. Thermodynamic guidelines for the design of bimetallic catalysts for oxygen electroreduction and rapid screening by scanning electrochemical microscopy. M-Co (M: Pd, Ag, Au)10.1021/ja0449729 ↗

41. High throughput correlative electrochemistry-microscopy analysis on a Zn-Al alloy10.1021/acsphyschemau.4c00016 ↗

42. Long‐range SECCM enables high‐throughput electrochemical screening of high entropy alloy electrocatalysts at up‐to‐industrial current densities10.1002/smtd.202301284 ↗

43. Co‐Cu materials library screening for discovering electrocatalysts for the co‐reduction of CO2 and nitrate to urea10.1002/ceur.202500333 ↗

44. Fast Li-ion storage and dynamics in TiO2 nanoparticle clusters probed by smart scanning electrochemical cell microscopy10.1002/anie.202214493 ↗

45. Accelerating the discovery of oxygen reduction electrocatalysts: high‐throughput screening of element combinations in Pt‐based high‐entropy alloys10.1002/anie.202407116 ↗

46. Accelerating the discovery of efficient high-entropy alloy electrocatalysts: high-throughput experimentation and data-driven strategies10.1021/acs.nanolett.4c03208 ↗

47. The new era of high-throughput nanoelectrochemistry10.1021/acs.analchem.2c05105 ↗

48. Experimental discovery of structure–property relationships in ferroelectric materials via active learning10.1038/s42256-022-00460-0 ↗

49. Evaluating the use of edge detection in extracting feature size from scanning electrochemical microscopy images10.1021/acs.analchem.8b05011 ↗

50. Smart material design via accelerated corrosion evaluation: convergence of high-throughput characterization and AI-driven prediction in marine engineering10.1038/s41529-025-00663-x ↗

51. Fast detection of micro-objects using scanning electrochemical microscopy based on visual recognition and machine learning10.1016/j.ultramic.2024.113937 ↗

52. Key requirements for advancing machine learning approaches in single entity electrochemistry

53. Probing electrocatalysis at individual Au nanorods via correlated optical and electrochemical measurements10.1021/acs.analchem.8b03360 ↗

54. Estimating pitting descriptors of 316 L stainless steel by machine learning and statistical analysis10.1038/s41529-023-00403-z ↗

55. Developing machine learning for heterogeneous catalysis with experimental and computational data10.1038/s41570-025-00740-4 ↗

56. Machine learning-driven nanoscale synthesis for electrocatalytic performance: from data-driven methodologies to closed-loop optimization10.1002/adma.202508263 ↗

57. Artificial-intelligence-driven scanning probe microscopy10.1038/s42005-020-0317-3 ↗

58. Autonomous scanning tunneling microscopy imaging via deep learning10.1021/jacs.4c11674 ↗

59. AI-equipped scanning probe microscopy for autonomous site-specific atomic-level characterization at room temperature10.1002/smtd.202400813 ↗

60. The emergence of automation in electrochemistry

61. Machine learning–accelerated design and synthesis of polyelemental heterostructures10.1126/sciadv.abj5505 ↗

62. Autonomous catalysis research with human–AI–robot collaboration10.1038/s41929-025-01430-6 ↗

63. Demonstration of an AI-driven workflow for autonomous high-resolution scanning microscopy10.1038/s41467-023-40339-1 ↗