journal article·2018-04

Cilia‐Inspired Flexible Arrays for Intelligent Transport of Viscoelastic Microspheres

Shuang Ben, Jun Tai, Han Ma, Yun Peng, Yuan Zhang, Dongliang Tian, Kesong Liu, Lei Jiang

Advanced Functional Materials· Volume 28· Issue 16
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Abstract

Abstract Anisotropic microstructures are widely used by being cleverly designed to achieve important functions. Mammals' respiratory tract is filled with dense cilia that rhythmically swing back and forth in a unidirectional wave to propel mucus and harmful substances out of the lung through larynx. Inspired by the ciliary structure and motion mechanism of the respiratory tract systems, a viscoelastic microsphere transporting strategy based on integration of airway cilium‐like structure and magnetically responsive flexible conical arrays is demonstrated. Under external magnetic fields, the viscoelastic microspheres can be directionally and continuously transported alongside the swing of the cilia‐like arrays that contain magnetic particles. This work provides a promising route for the design of advanced medical applications in directional transport of microspheres, drug delivery systems, ciliary dyskinesia treating, and self‐cleaning without liquid.
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Research context

OpenAlex topics: Micro and Nano Robotics · Genetic and Kidney Cyst Diseases · Advanced Materials and Mechanics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Key Laboratory of Bio‐Inspired Smart Interfacial Science and Technology of Ministry of Education School of Chemistry Beihang University Beijing 100191 P. R. China

Department of Otorhinolaryngology Head and Neck Surgery Beijing Key Laboratory for Pediatric Diseases of Otolaryngology Beijing Children's Hospital Beijing 100045 P. R. China

School of Materials Science and Engineering Beihang University Beijing 100191 China

Beijing Advanced Innovation Centre for Biomedical Engineering Beihang University Beijing 100191 China

Funding

Beijing Nova Program · Natural Science Foundation of Beijing Municipality · National Natural Science Foundation of China

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