Controlling Alveolar Bone Loss by Hydrogel‐Based Mitigation of Oral Dysbiosis and Bacteria‐Triggered Proinflammatory Immune Response (Adv. Funct. Mater. 3/2025)

Xiao Chen; Hanyao Huang; Chenyang Guo; Xuanzhi Zhu; Jiali Chen; Jinzheng Liang; Renjie Yang; Dan Shao; Fangman Chen; Bing Shi; Chao Yang; Kam W. Leong; Lei Zhao

doi:10.1002/adfm.202570014

journal article·2025-01Open access

Controlling Alveolar Bone Loss by Hydrogel‐Based Mitigation of Oral Dysbiosis and Bacteria‐Triggered Proinflammatory Immune Response (Adv. Funct. Mater. 3/2025)

Xiao Chen, Hanyao Huang, Chenyang Guo, Xuanzhi Zhu, Jiali Chen, Jinzheng Liang, Renjie Yang, Dan Shao, Fangman Chen, Bing Shi, Chao Yang, Kam W. Leong, Lei Zhao

Advanced Functional Materials· Volume 35· Issue 3

Publisher page Open full text

Source abstract

Abstract

MAMPs-Targeted Strategy In article number 2409121, Hanyao Huang, Chao Yang, Kam W. Leong, Lei Zhao, and co-workers propose a novel route for periodontitis treatment by applying a cationic hydrogel to capture microbial-associated molecular patterns to modulate bacteria-related proinflammatory response in the microenvironment.

Source: openalex_inverted_index · Quality: baseline

Research context

Polymers

OpenAlex topics: Oral microbiology and periodontitis research · Mesenchymal stem cell research · Oral health in cancer treatment

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases West China Hospital of Stomatology Sichuan University Chengdu Sichuan 610041 China

Department of Periodontics West China Hospital of Stomatology Sichuan University Chengdu Sichuan 610041 China

Department of Oral and Maxillofacial Surgery West China Hospital of Stomatology Sichuan University Chengdu Sichuan 610041 China

Department of Biomedical Engineering Columbia University New York NY 10027 USA

School of Biomedical Sciences and Engineering Guangzhou International Campus South China University of Technology Guangzhou 511442 China

Department of Orthopedics Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases The Third Affiliated Hospital of Southern Medical University Guangzhou 510630 China

Eastern Clinic West China Hospital of Stomatology Sichuan University Chengdu Sichuan 610041 China

School of Medicine South China University of Technology Guangzhou Guangdong 510006 China

National Engineering Research Center for Tissue Restoration and Reconstruction South China University of Technology Guangzhou Guangdong 510006 China

Department of Systems Biology Columbia University Medical Center New York NY 10032 USA

References

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