journal article·2026-03Open access

2D Conjugated Polymer Nanosheets: A New Choice for Boosting Electrochemiluminescence

Jingxian Li, Jing Fang, Ran Zhang, Dan Yang, Abing Duan, Run Li, Hongfen Yang, Ren Cai, Weihong Tan

Advanced Functional Materials· Volume 36· Issue 22

Abstract

Abstract The application of 2D conjugated polymers (2D CPs) in electrochemiluminescence (ECL) has been hindered due to their inherent flaws. Meanwhile, the weak ECL emission at the cathode is often ignored due to the poor conversion efficiency of O 2 to reactive oxygen species (ROS). To overcome these dilemmas, novel 2D conjugated polymer nanosheets (2D CPNs) are synthesized via a liquid‐liquid polymerization strategy to enhance ECL. The 2D CPNs exhibit effective catalytic active sites to facilitate the oxygen reduction reaction (ORR) performance, which are employed as a co‐reaction accelerator to promote the cathodic ECL in the luminol‐dissolved O 2 system. Importantly, the ECL signal is significantly amplified ≈50‐fold. It is found that the four‐electron (4e − ) pathway dominates the ORR process in an extremely narrow cathodic potential range. The ROS can participate in the chemical oxidization of luminol, which is confirmed by density functional theory calculations and in situ Raman tests. Moreover, a novel ECL sensor is designed for the ultra‐sensitive detection of the antioxidant catechol (CC) and would successfully distinguish with the isomers of CC. This work discovers the application of 2D conjugated polymers in the cathodic ECL of luminol and provides a new option to boost ECL for diverse requirements in practice.
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Research context

OpenAlex topics: Advanced biosensing and bioanalysis techniques · Electrochemical sensors and biosensors · Conducting polymers and applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Molecular Science and Biomedicine Laboratory State Key Laboratory of Chemo and Biosensing College of Chemistry and Chemical Engineering College of Biology College of Material Science and Engineering Hunan University Changsha Hunan 410082 P. R. China

Hunan Key Laboratory of Study and Discovery of Small Targeted Molecules School of Medicine Hunan Normal University Changsha Hunan 410013 P. R. China

Key Laboratory of Environmental Biology and Pollution Control Ministry of Education College of Environmental Science and Engineering Hunan University Changsha Hunan 410082 P. R. China

Department of Chemical Engineering The University of Western Australia Perth Western Australia 6009 Australia

Material Corrosion and Protection Key Laboratory of Sichuan Province Zigong Sichuan 643000 P. R. China

School of Public Health Hengyang Medical School University of South China Hengyang Hunan 421001 P. R. China

The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital) Institute of Hangzhou Medicine Chinese Academy of Sciences Hangzhou Zhejiang 310022 P. R. China

Institute of Molecular Medicine Renji Hospital Shanghai Jiao Tong University School of Medicine, and College of Chemistry and Chemical Engineering Shanghai Jiao Tong University Shanghai 200240 P. R. China

Funding

National Natural Science Foundation of China · Natural Science Foundation of Hunan Province

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