Recent progress in the design of G-quadruplex–based electrochemical aptasensors
Source abstract
Abstract
Abstract Aptamer-based electrochemical sensors are now developed for the detection of a wide variety of analytes including ions, low-molecular-weight molecules, proteins, and living cells. An aptamer-based sensor is an analytical device whose bio-sensing element (i.e. the aptamer) is immobilized on a transducer surface. Aptasensors have attracted great attention because of their high selectivity, sensitivity, and stability; they could be miniaturized and are of low production cost and offer extraordinary flexibility in the design of their assemblies. This review will emphasize recent developments of aptasensors using aptamers that are able to adopt the particular G-quadruplex (G4) conformations, which are secondary DNA structures formed from guanine-rich sequences. Indeed, G4 exhibits notable recognition properties inherent to their particular structuration.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Advanced biosensing and bioanalysis techniques · DNA and Nucleic Acid Chemistry · Molecular Junctions and Nanostructures
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (49)
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1. Recent advances in aptamer sensors10.3390/s21030979 ↗
2. A review: recent advances in ultrasensitive and highly specific recognition aptasensors with various detection strategies10.1016/j.ijbiomac.2020.03.173 ↗
3. Influence of aptamer surface coverage on small target recognition: a SPR and QCM-D comparative study10.1021/acs.jpcc.9b00845 ↗
4. G-Quadruplex-Forming aptamers-characteristics, applications, and perspectives10.3390/molecules24203781 ↗
5. Engineering light-up aptamers for the detection of RNA hairpins through kissing interaction10.1021/acs.analchem.0c01378 ↗
6. Sensor based on aptamer folding to detect low-molecular weight analytes10.1021/acs.analchem.5b01736 ↗
7. Impact of conformational transitions on SPR signals—theoretical treatment and application in small analytes/aptamer recognition10.1021/acs.jpcc.8b07298 ↗
8. Direct detection of low-molecular-weight compounds in 2D and 3D aptasensors by biolayer interferometry10.1021/acssensors.0c00925 ↗
9. Electrochemical aptasensor based on conductive supramolecular polymer hydrogels for thrombin detection with high selectivity10.1016/j.talanta.2019.120140 ↗
10. Quantification of EGFR and EGFR-overexpressed cancer cells based on carbon dots@bimetallic CuCo Prussian blue analogue10.1039/D0RA01439G ↗
11. Two-dimensional oriented growth of Zn-MOF-on-Zr-MOF architecture: a highly sensitive and selective platform for detecting cancer markers10.1016/j.bios.2018.09.079 ↗
12. Electrochemical aptamer-based sensor for real-time monitoring of insulin10.1021/acssensors.8b01573 ↗
13. DNA nanotetrahedron-assisted electrochemical aptasensor for cardiac troponin I detection based on the co-catalysis of hybrid nanozyme, natural enzyme and artificial DNAzyme10.1016/j.bios.2019.111578 ↗
14. Electrochemical aptasensors for cancer diagnosis in biological fluids - a review10.1016/j.aca.2020.04.022 ↗
15. Highly active DNAzyme-peptide hybrid structure coupled porous palladium for high-performance electrochemical aptasensing platform10.1016/j.snb.2017.12.091 ↗
16. A sensitive aptasensor based on a hemin/G-quadruplex-assisted signal amplification strategy for electrochemical detection of gastric cancer exosomes10.1002/smll.201900735 ↗
17. Label-free electrochemical detection of HepG2 tumor cells with a self-assembled DNA nanostructure-based aptasensor10.1016/j.snb.2018.04.142 ↗
18. Competitive multiple-mechanism-driven electrochemiluminescent detection of 8-Hydroxy-2’-deoxyguanosine10.1021/jacs.8b00515 ↗
19. Electrochemical determination of sulfamethazine using a gold electrode modified with multi-walled carbon nanotubes, graphene oxide nanoribbons and branched aptamers10.1007/s00604-020-04244-4 ↗
20. A novel visible light photoelectrochemical aptasensor for determination of bisphenol A based on surface plasmon resonance of gold nanoparticles activated g-C3N4 nanosheets10.1016/j.jelechem.2021.115122 ↗
21. Ultrasensitive aptasensor with DNA tetrahedral nanostructure for Ochratoxin A detection based on hemin/G-quadruplex catalyzed polyaniline deposition10.1016/j.snb.2018.08.072 ↗
22. Sensitivity enhancement of potassium ion (K+) detection based on graphene field-effect transistors with surface plasma pretreatment10.1016/j.snb.2019.01.058 ↗
23. Recent advances in the development of electrochemical aptasensors for detection of heavy metals in food10.1016/j.bios.2019.111777 ↗
24. A novel aptasensor based on 3D-reduced graphene oxide modified gold nanoparticles for determination of arsenite10.1016/j.bios.2018.09.034 ↗
25. Electrochemiluminescence aptasensor for multiple determination of Hg2+ and Pb2+ ions by using the MIL-53(Al)@CdTe-PEI modified electrode10.1016/j.aca.2019.11.069 ↗
26. A one-step dual-mode aptasensor for subnanomolar detection of lead ions based on electrochemiluminescence and fast scan voltammetry10.1149/1945-7111/abaf76 ↗
27. Construction of sandwiched self-powered biosensor based on smart nanostructure and capacitor: toward multiple signal amplification for thrombin detection10.1016/j.snb.2019.127418 ↗
28. Graphene-family materials in electrochemical aptasensors10.1007/s00216-020-02915-y ↗
29. Electrochemical aptasensor based on gold modified graphene nanocomposite with different morphologies for ultrasensitive detection of Pb2+10.1016/j.snb.2019.03.010 ↗
30. A bifunctional electrochemical aptasensor based on AuNPs-coated ERGO nanosheets for sensitive detection of adenosine and thrombin10.1007/s10008-021-04916-y ↗
31. An electrochemical thrombin aptasensor based on the use of graphite-like C3N4 modified with silver nanoparticles10.1007/s00604-020-4111-4 ↗
32. Electrochemical sensor based on molecularly imprinted polymer-aptamer hybrid receptor for voltammetric detection of thrombin10.1149/2.0131902jes ↗
33. An electrochemical aptasensor for detection of lead ions using a screen-printed carbon electrode modified with Au/polypyrrole composites and toluidine blue10.1039/C9AY01256G ↗
34. Graphene-based aptasensors: from molecule-interface interactions to sensor design and biomedical diagnostics10.1039/C8AN00081F ↗
35. A novel label-free electrochemical aptasensor with one-step assembly process for rapid detection of lead (II) ions10.1016/j.snb.2020.128326 ↗
36. Improved binding induced self-assembled DNA to achieve ultrasensitive electrochemical proximity assay10.1016/j.snb.2019.127278 ↗
37. Hairpin DNA assisted dual-ratiometric electrochemical aptasensor with high reliability and anti-interference ability for simultaneous detection of aflatoxin B1 and ochratoxin A10.1016/j.bios.2020.112654 ↗
38. An electrochemical aptasensor based on gold nanoparticles and graphene oxide doped poly(3,4-ethylenedioxythiophene) nanocomposite for detection of MUC110.1016/j.jelechem.2018.02.014 ↗
39. A highly sensitive electrochemical aptasensor for detection of microcystin-LR based on a dual signal amplification strategy10.1039/C8AN01971A ↗
40. Electrochemical sandwich-type thrombin aptasensor based on silver nanowires& particles decorated electrode and the signal amplifier of Pt loaded hollow zinc ferrite10.1016/j.colsurfa.2020.125804 ↗
41. An impedimetricAptasensor based on a novel line-pad-line electrode for the determination of VEGF(165)10.1002/elan.202060030 ↗
42. Electrochemical aptasensor based on a potassium ion-triggered DNA conformation transition and self-assembly on an electrode10.1039/C9NJ00158A ↗
43. Sensitive and label-free electrochemical lead ion biosensor based on a DNAzyme triggered G-quadruplex/hemin conformation10.1016/j.bios.2018.04.054 ↗
44. Development of novel and highly specific ssDNA-aptamer-based electrochemical biosensor for rapid detection of mercury (II) and lead (II) ions in water10.3390/chemosensors7020027 ↗
45. A novel modification-free thrombin electrochemical sensing based homogeneous strategy10.1016/j.snb.2020.128045 ↗
46. A highly sensitive VEGF165 photoelectrochemical biosensor fabricated by assembly of aptamer bridged DNA networks10.1016/j.bios.2017.10.032 ↗
47. DNA-enhanced peroxidase activity of a DNA aptamer-hemin complex10.1016/S1074-5521(98)90006-0 ↗
48. Peroxidase-mimicking DNAzymes for biosensing applications: a review10.1016/j.aca.2011.08.050 ↗
49. Amplified biosensing using the horseradish peroxidase-mimicking DNAzyme as an electrocatalyst10.1021/ac100095u ↗