Progress in single-biomolecule analysis with solid-state nanopores
Source abstract
Abstract
Summary Solid-state nanopores and nanopipettes are a new class of stochastic, single-molecule sensors that have now reached a certain degree of maturity. While DNA sequencing has been a major driving force in the field of nanopore sensing since the early 1990s, a feat that has now been achieved with modified biological pores, new potential applications emerge, in particular for solid-state devices. These capitalize on some of the advantages of solid-state pores over their biological counterparts as well as recent technological advances and progress in our fundamental understanding of the translocation process. Here, we will discuss and highlight some of these developments with particular focus on single-molecule analysis of and structures based on double-stranded DNA.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Nanopore and Nanochannel Transport Studies · RNA Interference and Gene Delivery · Advanced biosensing and bioanalysis techniques
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (44)
Show source-provided references
1. Three decades of nanopore sequencing10.1038/nbt.3423 ↗
2. Challenges in DNA motion control and sequence readout using nanopore devices10.1088/0957-4484/26/7/074004 ↗
3. DNA sequencing by nanopores: advances and challenges10.1088/0022-3727/49/41/413001 ↗
4. Solid-state and biological nanopore for real-time sensing of single chemical and sequencing of DNA10.1016/j.nantod.2012.12.008 ↗
5. Ion-beam sculpting at nanometre length scales10.1038/35084037 ↗
6. DNA molecules and configurations in a solid-state nanopore microscope10.1038/nmat965 ↗
7. Detecting DNA folding with nanocapillaries10.1021/nl100997s ↗
8. G.A.T. Chansin, R. Mulero, J. Hong, M.J. Kim, A.J. deMello, J.B. Edel, “Single-molecule spectroscopy using nano-porous membranes”, Nano Lett. 2007, 7, 2901–2906.10.1021/nl071855d ↗
9. Optical recognition of converted DNA nucleotides for single-molecule DNA sequencing using nanopore arrays10.1021/nl1012147 ↗
10. Pitchford WH, Kim H-J, Ivanov AP, Kim H-M, Yu J-S, Leatherbarrow RJ, Albrecht T, Kim K-B, Edel JB, “Synchronized optical and electronic detection of biomolecules using a low noise nanopore platform”, ACS Nano 2015, 9, 1740–1748.10.1021/nn506572r ↗
11. Rapid ultrasensitive single particle surface-enhanced raman spectroscopy using metallic nanopores10.1021/nl402108g ↗
12. DNA tunneling detector embedded in a nanopore10.1021/nl103873a ↗
13. Translocation of RecA-coated double-stranded DNA through solid-state nanopores10.1021/nl803189k ↗
14. DNA profilking using solid-state nanopores: detection of DNA-binding molecules10.1021/nl901691v ↗
15. Nanopore based sequence specific detection of duplex DNA for genomic profiling10.1021/nl100058y ↗
16. Electronic barcoding of a viral gene at the single-molecule level10.1021/nl300372a ↗
17. SSB binding to single-stranded DNA probed using solid-state nanopore sensors10.1021/jp506832u ↗
18. Single-molecule studies of unlabeled full-length p53 protein binding to DNA10.1021/acs.jpcb.5b11076 ↗
19. Detection of individual proteins bound along DNA using solid-state nanopores10.1021/acs.nanolett.5b00249 ↗
20. Nanopore-based assay for detection of methylation in double-stranded DNA fragments
21. J.S. Yu, M.-C. Lim, D.T. Ngoc Huynh, H.-J. Kim, H.-M. Kim, Y.-R. Kim, K.-B. Kim, “Identifying the location of a single protein along the DNA strand using solid-state nanopores” ACS Nano 2015, 9, 5289–5298.10.1021/acsnano.5b00784 ↗
22. Direct observation of DNA knots using a solid-state nanopore10.1038/nnano.2016.153 ↗
23. Velocity of DNA during translocation through a solid-state nanopore10.1021/nl504375c ↗
24. Digitally encoded DNA nanostructures for multiplexed, single-molecule protein sensing with nanopores10.1038/nnano.2016.50 ↗
25. Single molecule based SNP detection using designed DNA carriers and solid-state nanopores10.1039/C6CC08621G ↗
26. DNA translocation through graphene nanopores10.1021/nl101046t ↗
27. Graphene as a subnanometre trans-electrode membrane10.1038/nature09379 ↗
28. DNA translocation through graphene nanopores10.1021/nl102069z ↗
29. Flexibility of DNA10.1146/annurev.bb.17.060188.001405 ↗
30. The persistence length of double stranded DNA determined using dark field tethered particle motion10.1063/1.3142699 ↗
31. Electrostatic focusing of unlabelled DNA into nanoscale pores using a salt gradient10.1038/nnano.2009.379 ↗
32. Effect of salt concentration on the electrophoretic speed of a polyelectrolyte through a nanopore10.1103/PhysRevLett.98.238104 ↗
33. DNA translocation governed by interactions with solid-state nanopores
34. High-speed detection of DNA translocation in nanopipettes10.1039/C5NR08634E ↗
35. On the distribution of DNA translocation times in solid-state nanopores: an analysis using Schrödinger's first-passage-time theory10.1088/0953-8984/25/37/375102 ↗
36. Origins and consequences of velocity fluctuations during DNA passage through a nanopore10.1016/j.bpj.2011.05.034 ↗
37. Performance assessment of DNA fragment sizing by high-sensitivity flow cytometry and pulsed-field gel electrophoresis10.1128/JCM.42.5.1965-1976.2004 ↗
38. Single molecule ionic current sensing in segmented flow microfluidics10.1021/ac403921m ↗
39. Instrumentation for low-noise high-bandwidth nanopore recording, Chapter 3
40. Integrated nanopore sensing platform with sub-microsecond temporal resolution10.1038/nmeth.1932 ↗
41. Measurement of DNA translocation dynamics in a solid-state nanopore at 100 ns temporal resolution10.1021/acs.nanolett.6b01661 ↗
42. High-bandwidth detection of short DNA in nanopipettes10.1039/C6FD00109B ↗
43. Specific protein detection using designed DNA carriers and nanopores10.1021/ja512521w ↗
44. Wafer-scale ion beam lithography of nanopore devices10.1017/S1431927613006557 ↗