journal article·2025-06Open access

Top‐Down Assembly of Photosensitizable Flexible Wood Dressing with Synergistic Effect of Anti‐Infection and Moisture Management

Siqi Huang, Zaiyu Wang, Qian Wu, Bo Wu, Binbin Chen, Ying Li, Zijie Qiu, Zheng Zhao, Ben Zhong Tang

Advanced Functional Materials· Volume 35· Issue 26

Abstract

Abstract Infected wound repair stands as a formidable global issue, posing significant threats to public health and medical care. Biopolymer‐based dressings represent a natural and biocompatible candidate greatly conductive to wound healing. However, the low productivity and high price, coupled with the widespread lack of antibacterial activities, vitally restrict their clinical applications. Herein, a simple yet efficient top‐down assembly strategy is reported to fabricate aggregation‐induced emission photosensitizer (AIE‐PS) functionalized flexible wood (AIE/FW) dressing with synergistic photodynamic therapy and moisture management to accelerate the healing of infected wounds. On account of its superior bactericidal effectiveness and appropriate moisture management, along with superb flexibility and excellent biocompatibility, the proposed AIE/FW can effectively prevent wound infection and alleviate inflammatory response, thereby dramatically boosting the infected wound recovery. It is anticipated that the scalable, sustainable, and cost‐effective AIE/FW offers a promising pathway to overcome global wound care challenges.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Additive Manufacturing and 3D Printing Technologies · Surface Modification and Superhydrophobicity · Wound Healing and Treatments

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Science and Engineering Shenzhen Institute of Aggregate Science and Technology The Chinese University of Hong Kong Shenzhen Guangdong 518172 P. R. China

Department of Chemistry Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction The Hong Kong University of Science and Technology Kowloon Hong Kong 999077 China

Faculty of Materials Science Shenzhen MSU‐BIT University Shenzhen Guangdong 518100 China

Innovation Research Center for AIE Pharmaceutical Biology Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology the NMPA and State Key Laboratory of Respiratory Disease School of Pharmaceutical Sciences Guangzhou Medical University Guangzhou Guangdong 511436 China

Funding

National Key Research and Development Program of China · National Natural Science Foundation of China · Innovation and Technology Commission

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