journal article·2024-09Open access

Carbon‐Based Nanomaterials for Antiviral Applications

Ángel Serrano‐Aroca, Kazuo Takayama, Yogendra Kumar Mishra, Cesar de la Fuente‐Nunez

Advanced Functional Materials· Volume 34· Issue 38

Abstract

Abstract In the antimicrobial resistance era, carbon‐based nanomaterials (CBNs) such as fullerenes, carbon dots, graphene, and their derivatives are promising therapeutic tools in combating viral diseases. This review shows that these materials have broad‐spectrum antiviral activity against 33 viruses belonging to different Baltimore groups. CBNs also exhibit antimicrobial activity against bacteria and fungi and possess a low risk of selecting for resistance, since their primary mode of antimicrobial action involves physically damaging the microbes. CBNs also offer additional promising properties, including enhanced antiviral effectiveness under diverse types of irradiation and facilitating antiviral immune responses. Their potential as antiviral agents is still in its infancy and future research should focus on their toxicity, antiviral mechanisms, pharmacokinetics, and bioavailability. They are also potential antiviral materials for preventing the transmission of viral diseases for use in face masks, shields, hospital and airport surfaces, and elevators, among others. It is anticipated that CBNs will play an increasingly significant role in the fight against viruses and infectious diseases.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Graphene and Nanomaterials Applications · Carbon and Quantum Dots Applications · Graphene research and applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Biomaterials and Bioengineering Lab Centro de Investigación Traslacional San Alberto Magno Universidad Católica de Valencia San Vicente Mártir Valencia 46001 Spain

Center for iPS Cell Research and Application (CiRA) Kyoto University Kyoto 606‐8397 Japan

University of Southern Denmark Mads Clausen Institute NanoSYD, Alsion 2 Sønderborg 6400 Denmark

Machine Biology Group Departments of Psychiatry and Microbiology Institute for Biomedical Informatics Institute for Translational Medicine and Therapeutics Perelman School of Medicine University of Pennsylvania Philadelphia PA 19104 USA

Departments of Bioengineering and Chemical and Biomolecular Engineering School of Engineering and Applied Science University of Pennsylvania Philadelphia PA 19104 USA

Department of Chemistry School of Arts and Sciences University of Pennsylvania Philadelphia PA 19104 USA

Penn Institute for Computational Science University of Pennsylvania Philadelphia PA 19104 USA

Funding

Ministerio de Ciencia e Innovación

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