DataVXAdvanced Functional MaterialsPaper
journal article·2023-09Open access

3D Printed Template‐Assisted Casting of Biocompatible Polyvinyl Alcohol‐Based Soft Microswimmers with Tunable Stability

Roger Sanchis‐Gual, Hao Ye, Towa Ueno, Fabian C. Landers, Lukas Hertle, Siyu Deng, Andrea Veciana, Yanming Xia, Carlos Franco, Hongsoo Choi, Josep Puigmartí‐Luis, Bradley J. Nelson, Xiang‐Zhong Chen, Salvador Pané

Advanced Functional Materials· Volume 33· Issue 39
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Source abstract

Abstract

Abstract The past decade has seen an upsurge in the development of small‐scale magnetic robots for various biomedical applications. However, many of the reported designs comprise components with biocompatibility concerns. Strategies for fabricating biocompatible and degradable microrobots are required. In this study, polyvinyl alcohol (PVA)‐based magnetic hydrogel microrobots with different morphologies and tunable stability are developed by combining a 3D printed template‐assisted casting with a salting‐out process. 3D sacrificial micromolds are prepared via direct laser writing to shape PVA‐magnetic nanoparticle composite hydrogel microrobots with high architectural complexity. By adjusting the PVA composition and salting‐out parameters, the hydrogel dissolubility can be customized. Due to their high mobility, tunable stability, and high biocompatibility, these PVA‐based magnetic microrobots are suitable platforms for targeted drug and cell delivery.
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Research context

PolymersNanomaterialsBiomaterialsCompositesMaterials processing

OpenAlex topics: Micro and Nano Robotics · Advanced Materials and Mechanics · Modular Robots and Swarm Intelligence

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Multi‐Scale Robotics Lab Institute of Robotics and Intelligent Systems ETH Zürich Tannenstrasse 3 Zürich CH‐8092 Switzerland

Department of Mechanical & Electrical Engineering Xiamen University Xiamen 361005 China

Department of Robotics and Mechatronics Engineering DGIST‐ETH Microrobot Research Center Daegu‐Gyeongbuk Institute of Science & Technology (DGIST) 333 Techno jungang‐daero Hyeonpung‐eup, Dalseong‐gun Daegu 42988 Republic of Korea

Departament de Ciència dels Materials i Química Física Institut de Química Teòrica i Computacional University of Barcelona (UB) Barcelona 08028 Spain

ICREA Institució Catalana de Reserca i Estudis Avançats Pg. Lluís Companys 23 Barcelona 08010 Spain

Funding

National Research Foundation of Korea · Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung · Ministerio de Ciencia, Innovación y Universidades · H2020 European Research Council

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