journal article·2021-12

Immune Cycle‐Based Strategies for Cancer Immunotherapy

Yanhua Li, Xiaohan Liu, Xia Zhang, Wei Pan, Na Li, Bo Tang

Advanced Functional Materials· Volume 31· Issue 50
Publisher page

Abstract

Abstract The immune system is composed of immune organs, immune cells, and immunoactive substances, which plays a vital role in antitumor immunity in cancer immunotherapy. During the process of the antitumor immune response, many factors are involved in the cancer immune cycle. Therefore, developing intelligent strategies based on the steps of the cancer immune cycle to elicit the immune responses for enhanced cancer immunotherapy is of great significance. In this review, the key factors in each step of the cancer immune cycle are discussed, and then, the intelligent therapeutic strategies for modulating the immune surveillance against cancer are highlighted. Considering the demand for cancer immunotherapy in clinic, some suggestions for constructing new intelligent strategies are also put forward, which will make antitumor immunity more effective and advance the development of cancer immunotherapy.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Immunotherapy and Immune Responses · Cancer Immunotherapy and Biomarkers · Immune cells in cancer

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

College of Chemistry Chemical Engineering and Materials Science Key Laboratory of Molecular and Nano Probes Ministry of Education Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong Institute of Molecular and Nano Science Shandong Normal University Jinan 250014 P. R. China

Funding

National Natural Science Foundation of China

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