Source abstract
Abstract
Abstract Electric signal accelerates full‐thickness wound healing in the clinic, which is usually generated by a large power generation system and requires delicate control by authorized personnel. Here, a self‐powered flexible and biocompatible thermoelectric device with exceptionally high power generation efficiency is developed. It generates 10 mV voltage at a temperature gradient of 10 K, outperforming all reported flexible thermoelectric devices. Accordingly, it can directly and efficiently convert the omnipresent heat in the skin to electricity at the microvolt level. The output electricity activates and upregulates the expression of Piezo1‐mediated pathways that are associated with tissue regeneration, accelerating the cell migration and proliferation in vitro and healing the wound 4 days faster in vivo. Importantly, the thermoelectric device fast‐heals the wound without involving any additional electric circuit such as an amplifier. These advantages will revolutionize the designing of self‐powered wearable bioelectronics for diagnosing, monitoring, and treating various pathological conditions employing the skin heat.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Planarian Biology and Electrostimulation · Thermal Radiation and Cooling Technologies · Advanced Thermoelectric Materials and Devices
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research College of Stomatology Xi'an Jiaotong University Xi'an 710004 China
State Key Laboratory of Solidification Processing Northwestern Polytechnical University Xi'an 710072 China
Shenzhen Institute of Advanced Electronic Materials Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China
Shenzhen Institute for Advanced Study University of Electronic Science and Technology of China Shenzhen 518110 China
State Key Laboratory of Oral Diseases National Clinical Research Center for Oral Diseases West China Hospital of Stomatology Sichuan University Chengdu Sichuan 610041 China
Funding
National Natural Science Foundation of China
References (34)
Show source-provided references
4. Kranke P. · Cochrane Database Syst. Rev. · 2015 · 6