journal article·2023-02Open access

Marine‐Derived Hydrogels for Biomedical Applications

Xiang Lin, Jinglin Wang, Xiangyi Wu, Yuan Luo, Yongan Wang, Yuanjin Zhao

Advanced Functional Materials· Volume 33· Issue 6

Abstract

Marine organisms provide novel and broad sources for the preparations and applications of biomaterials. Since the urgent requirement of bio‐hydrogels to mimic tissue extracellular matrix (ECM), the natural biomacromolecule hydrogels derived from marine sources have received increasing attention. Benefiting from their outstanding bioactivity and biocompatibility, many attempts have been made to reconstruct ECM components by applying marine‐derived natural hydrogels. Moreover, marine hydrogels have been successfully applied in biomedicine by means of microfluidics, electrospray, and bioprinting. In this review, the classification and characteristics of marine‐derived hydrogels are summarized. In particular, their role in the development of biomaterials is also introduced. Then, the recent advances in bio‐fabrication strategies for various hydrogel materials are focused upon. Besides, the influences of hydrogel types on their functions in biomedical applications are discussed in depth. Finally, critical reflections on the limitations and future development of marine‐derived hydrogels are presented.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: 3D Printing in Biomedical Research · Electrospun Nanofibers in Biomedical Applications · Electrohydrodynamics and Fluid Dynamics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Rheumatology and Immunology Nanjing Drum Tower Hospital School of Biological Science and Medical Engineering Southeast University Nanjing 210096 China

State Key Laboratory of Toxicology and Medical Countermeasures Beijing Institute of Pharmacology and Toxicology Beijing 100850 China

Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine Vision and Brain Health) Wenzhou Institute University of Chinese Academy of Sciences Wenzhou Zhejiang 325001 China

Funding

National Key Research and Development Program of China · National Natural Science Foundation of China · Shenzhen Fundamental Research Program

References (100+)

Show source-provided references
1. 10.1038/s41467-021-22802-z10.1038/s41467-021-22802-z ↗
2. 10.1038/s41467-021-21029-210.1038/s41467-021-21029-2 ↗
3. 10.1038/s41467-021-20953-710.1038/s41467-021-20953-7 ↗
4. 10.1126/sciadv.abd371610.1126/sciadv.abd3716 ↗
5. 10.1007/s11431-020-1731-810.1007/s11431-020-1731-8 ↗
6. 10.1007/s11431-020-1735-910.1007/s11431-020-1735-9 ↗
7. 10.1016/j.cej.2022.13790710.1016/j.cej.2022.137907 ↗
8. 10.1016/j.bioactmat.2022.03.03210.1016/j.bioactmat.2022.03.032 ↗
9. 10.1016/j.cej.2022.13841710.1016/j.cej.2022.138417 ↗
10. 10.1016/j.cej.2022.13825710.1016/j.cej.2022.138257 ↗
11. Wu S. W. · NPG Asia Mater. · 2022 · 14 · 126431
12. 10.1038/s41467-022-29037-610.1038/s41467-022-29037-6 ↗
13. 10.1002/smtd.20210151310.1002/smtd.202101513 ↗
14. 10.1039/D1RA08447J10.1039/D1RA08447J ↗
15. 10.1039/D2TB00591C10.1039/D2TB00591C ↗
16. 10.1002/advs.20210600810.1002/advs.202106008 ↗
17. 10.1021/acs.chemmater.1c0278110.1021/acs.chemmater.1c02781 ↗
18. 10.1002/adhm.20220039310.1002/adhm.202200393 ↗
19. 10.1038/s41563-021-01136-710.1038/s41563-021-01136-7 ↗
20. 10.1016/j.carpta.2022.10020210.1016/j.carpta.2022.100202 ↗
21. 10.1039/D2QM00469K10.1039/D2QM00469K ↗
22. 10.1007/s12274-022-4089-910.1007/s12274-022-4089-9 ↗
23. 10.1007/s11274-010-0415-610.1007/s11274-010-0415-6 ↗
24. 10.3390/md1910057210.3390/md19100572 ↗
25. 10.1016/j.biortech.2020.12336210.1016/j.biortech.2020.123362 ↗
26. 10.1016/j.bioactmat.2021.04.02810.1016/j.bioactmat.2021.04.028 ↗
27. 10.1002/fsn3.247110.1002/fsn3.2471 ↗
28. 10.1080/10408398.2012.68693310.1080/10408398.2012.686933 ↗
29. 10.1002/advs.20220122610.1002/advs.202201226 ↗
30. 10.1021/acsabm.1c0068510.1021/acsabm.1c00685 ↗
31. 10.1088/1748-605X/abf0b610.1088/1748-605X/abf0b6 ↗
32. 10.3390/md1909050210.3390/md19090502 ↗
33. 10.1016/j.cej.2022.13725910.1016/j.cej.2022.137259 ↗
34. Yamakita T. · Front. Biosci.‐Landmark · 2022 · 9 · 823009
35. 10.3390/md1908040310.3390/md19080403 ↗
36. 10.1080/14786419.2020.174158310.1080/14786419.2020.1741583 ↗
37. Yu H. B. · Chem. Biodivers. · 2022 · 19
38. 10.1016/j.oraloncology.2022.10597110.1016/j.oraloncology.2022.105971 ↗
39. 10.3390/molecules2707235110.3390/molecules27072351 ↗
40. Arroba A. I. · Eur. J. Ophthalmol. · 2022 · 32 · 21
41. Solis X. · Chem. Inst. Can. Am. Chem. Soc. · 2019 · 257 · 47
42. 10.2174/138161282866622032812253910.2174/1381612828666220328122539 ↗
43. 10.1002/term.150610.1002/term.1506 ↗
44. 10.3390/md1708046710.3390/md17080467 ↗
45. 10.3390/md1910056310.3390/md19100563 ↗
46. Sundar G. · Polym. Bull. · 2022 · 5 · 04347
47. 10.1016/S0169-409X(97)00125-710.1016/S0169-409X(97)00125-7 ↗
48. Atma Y. · Biointerface Res. Appl. Chem. · 2022 · 12 · 3966
49. 10.1016/S0142-9612(03)00096-610.1016/S0142-9612(03)00096-6 ↗
50. 10.1088/1758-5090/aa83cf10.1088/1758-5090/aa83cf ↗
51. 10.1016/j.tifs.2019.02.04810.1016/j.tifs.2019.02.048 ↗
52. 10.1038/s41467-022-30691-z10.1038/s41467-022-30691-z ↗
53. 10.1007/s41061-021-00360-810.1007/s41061-021-00360-8 ↗
54. 10.1016/j.chemosphere.2020.12893410.1016/j.chemosphere.2020.128934 ↗
55. 10.1080/10717544.2021.201852110.1080/10717544.2021.2018521 ↗
56. Li X. Q. · Food Hydrocolloid · 2023 · 134
57. 10.1016/j.bioactmat.2022.04.03210.1016/j.bioactmat.2022.04.032 ↗
58. 10.1016/j.foodhyd.2022.10809410.1016/j.foodhyd.2022.108094 ↗
59. 10.1021/acsnano.8b0623710.1021/acsnano.8b06237 ↗
60. 10.1016/j.bioactmat.2020.02.00410.1016/j.bioactmat.2020.02.004 ↗
61. 10.1016/S0142-9612(00)00201-510.1016/S0142-9612(00)00201-5 ↗
62. 10.1038/nature1140910.1038/nature11409 ↗
63. 10.1021/acs.biomac.9b0140110.1021/acs.biomac.9b01401 ↗
64. 10.1126/sciadv.abj951310.1126/sciadv.abj9513 ↗
65. 10.1126/science.abm973510.1126/science.abm9735 ↗
66. 10.1007/s11426-022-1330-y10.1007/s11426-022-1330-y ↗
67. 10.1038/s41586-020-2612-210.1038/s41586-020-2612-2 ↗
68. 10.1021/acs.biomac.9b0096510.1021/acs.biomac.9b00965 ↗
69. 10.1126/science.abi970210.1126/science.abi9702 ↗
70. 10.1126/science.114724110.1126/science.1147241 ↗
71. 10.1021/acsnano.1c0272010.1021/acsnano.1c02720 ↗
72. 10.1002/adma.20210893110.1002/adma.202108931 ↗
73. 10.1016/j.bioactmat.2021.06.03110.1016/j.bioactmat.2021.06.031 ↗
74. 10.1002/anbr.20210003510.1002/anbr.202100035 ↗
75. 10.1021/acsabm.1c0105210.1021/acsabm.1c01052 ↗
76. 10.1088/1758-5090/ac1e7810.1088/1758-5090/ac1e78 ↗
77. De Santis M. M. · Adv. Mater. · 2021 · 33
78. 10.1038/s41467-022-31002-210.1038/s41467-022-31002-2 ↗
79. 10.1126/sciadv.abk179210.1126/sciadv.abk1792 ↗
80. 10.1126/sciadv.abe288810.1126/sciadv.abe2888 ↗
81. 10.1126/sciadv.abi629010.1126/sciadv.abi6290 ↗
82. 10.1002/advs.20210121010.1002/advs.202101210 ↗
83. 10.34133/2020/367212010.34133/2020/3672120 ↗
84. 10.1039/D1LC00450F10.1039/D1LC00450F ↗
85. 10.1038/s41578-019-0148-610.1038/s41578-019-0148-6 ↗
86. 10.1002/smll.20200659610.1002/smll.202006596 ↗
87. 10.1126/sciadv.aat281610.1126/sciadv.aat2816 ↗
88. 10.1038/s41578-018-0077-910.1038/s41578-018-0077-9 ↗
89. 10.1038/s41596-018-0051-410.1038/s41596-018-0051-4 ↗
90. 10.1002/adma.20140079810.1002/adma.201400798 ↗
91. 10.1021/acsami.5b1144510.1021/acsami.5b11445 ↗
92. 10.1002/adma.20200675910.1002/adma.202006759 ↗
93. 10.1088/1748-605X/aa7b5510.1088/1748-605X/aa7b55 ↗
94. 10.1088/1748-605X/abef7b10.1088/1748-605X/abef7b ↗
95. 10.1039/D1BM00809A10.1039/D1BM00809A ↗
96. 10.1002/adma.20190783310.1002/adma.201907833 ↗
97. 10.1002/adfm.20180138610.1002/adfm.201801386 ↗
98. 10.1002/adma.20220391510.1002/adma.202203915 ↗
99. 10.1039/C8MH00647D10.1039/C8MH00647D ↗
100. 10.1016/j.ijpharm.2021.12074910.1016/j.ijpharm.2021.120749 ↗