Concentration Gradients in Material Sciences: Methods to Design and Biomedical Applications
Source abstract
Abstract
Abstract Concentration gradients are at the basis of many natural phenomena and hold great importance in human and plant biology. This basic phenomenon has inspired many material scientists to confer novel and original properties to materials with numerous biomedical and pharmaceutical applications such as drug discovery, controlled release of drugs, tissue engineering, orthopedic implants and time–temperature indicators, amongst others. While the generation of gradients in solution is well described, their incorporation in solid materials remains challenging. This study reviews concepts and methods reported to generate gradients in respective solutions and (at the surface or in) solid materials like polymer scaffolds and matrices. This article also discusses how innovative materials possessing such gradients may be applied in biomedicine and pharmacy.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: 3D Printing in Biomedical Research · Bone Tissue Engineering Materials · Graphene and Nanomaterials Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Joint Laboratory of Advanced Biomedical Materials (NFU‐UGent) College of Chemical Engineering Nanjing Forestry University (NFU) Nanjing 210037 P. R. China
Laboratory of General Biochemistry and Physical Pharmacy Faculty of Pharmaceutical Sciences Ghent University Ghent 9000 Belgium
TIPs (Transfers, Interfaces and Processes) Université Libre de Bruxelles Brussels 1050 Belgium
Funding
National Natural Science Foundation of China · National Basic Research Program of China · Priority Academic Program Development of Jiangsu Higher Education Institutions · Doctorate Fellowship Foundation of Nanjing Forestry University
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