journal article·2024-11Open access

Evaluating Laser‐Based Microfabrication in Microfluidics: An Experimental and Computational Trial

Alice Betti, Claudio Ongaro, Barbara Zardin, Jessika Bertacchini, Nadia Tagliaferri, Vincenzina Siciliani, Leonardo Orazi, Massimo Borghi

Advanced Engineering Materials· Volume 26· Issue 21

Abstract

The aim of this research is to validate a new prototyping method for microfluidic devices which could compete with the widely used polydimethylsiloxane soft lithography. This alternative methodology uses laser‐etched glass and pre‐cured silicone as main materials. A dual approach is chosen for validation, testing prototypes of a mixing device well known in the scientific literature. Specifically the focus is to evaluate the mixing efficiency (ME) of two fluids flowing through the device. After fine‐tuning the fabrication process, the ME is experimentally evaluated, and the results are compared with a 3D computational fluid dynamic analysis.
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Research context

OpenAlex topics: Microfluidic and Capillary Electrophoresis Applications · 3D Printing in Biomedical Research · Microfluidic and Bio-sensing Technologies

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Engineering Department Enzo Ferrari DIEF University of Modena and Reggio Emilia via P. Vivarelli 10 Modena 41125 Italy

Department of Surgery, Medicine, Dentistry and Morphological Sciences with Interest in Transplant, Oncology and Regenerative Medicine CHIMOMO via del Pozzo 71 Modena 41125 Italy

Department of Sciences and Methods for Engineering DISMI University of Modena and Reggio Emilia via Amendola 2, Pad. Morselli Reggio Emilia 42122 Italy

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