journal article·2021-06

Hollow Microneedle Arrays Produced by Low‐Cost, High‐Fidelity Replication of Hypodermic Needle Tips for High‐Dose Transdermal Drug Delivery

Cuiping Zhou, Hao Tang, Li Zhang, Hong An, Yunjin Wu, Ding Tang, Jianhua Zhou

Advanced Engineering Materials· Volume 23· Issue 6
Publisher page

Abstract

Hollow microneedle arrays (HMN), which exhibit advantages like safety in use, painlessness, high drug loading, precise administration and convenience of connecting to external devices, have been massively produced via a simple, low-cost and high-fidelity replication strategy. The as-obtained HMN could be integrated onto a microfluidic chip with different microchannels, and the microfluidic chip could be further applied to fabricate a bundle device by attaching the chip to a looped zip tie. By using this zip tie, vaccines or drugs could be loaded in a convenient way, as described in the article, number 2001355, by Jianhua Zhou and co-workers.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Advancements in Transdermal Drug Delivery · Microfluidic and Capillary Electrophoresis Applications · Lipid Membrane Structure and Behavior

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Emergency Nanfang Hospital Southern Medical University Guangzhou 510515 China

Division of Engineering in Medicine Department of Medicine Brigham and Women's Hospital Harvard Medical School Cambridge MA 02139 USA

Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province School of Biomedical Engineering Sun Yat-sen University Guangzhou 510275 China

References

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