Fabrication and Evaluation of Chitin‐Based Nerve Guidance Conduits Used to Promote Peripheral Nerve Regeneration

Chitin product was prepared from the chitosan counterpart and both were found to be equally biocompatible with cultured Schwann cells. Chitin- and chitosan-based nerve guidance conduits (NGCs) were surgically implanted to bridge 10-mm-long neural defects in rat sciatic nerves. The regenerative outcome provided positive evidence that chitin- and chitosan-based NGCs produce the similar beneficial effects on peripheral nerve regeneration.