Sample Geometry Influences the Outcome of in vitro Cytotoxicity Tests
Source abstract
Abstract
Cytotoxicity of materials is tested in vitro according to standards detailed in ISO 10993. Since ISO 10993 allows a wide range of experimental conditions a material might be judged to be non cytotoxic or cytotoxic depending on the choice of sample geometry. Two cytotoxicity test systems were compared with each other. It is recommended that test conditions should be simplified in order to make cytotoxicity results more transparent.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Animal testing and alternatives · Effects and risks of endocrine disrupting chemicals · 3D Printing in Biomedical Research
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (11)
Show source-provided references
1. ISO_10993‐5 Vol. ISO 10993‐5:1999(E) International Organization for Standardization 1999.
2. ISO_10993‐12 Vol. ISO 10993‐12:2002(E) International Organization for Standardization 2002.
3. 10.1016/j.biomaterials.2004.05.02510.1016/j.biomaterials.2004.05.025 ↗
4. 10.1002/jat.104110.1002/jat.1041 ↗
5. 10.1111/j.0143-2885.2004.00779.x10.1111/j.0143-2885.2004.00779.x ↗
6. 10.1016/S0109-5641(02)00081-710.1016/S0109-5641(02)00081-7 ↗
7. 10.1002/jbm.b.3067610.1002/jbm.b.30676 ↗
8. 10.1016/j.dental.2006.11.02010.1016/j.dental.2006.11.020 ↗
9. 10.1177/15440591060850100110.1177/154405910608501001 ↗
10. ISO_10993‐12 Vol. ISO 10993‐12:2007(E) International Organization for Standardization 2007.
11. 10.1016/j.dental.2007.05.01410.1016/j.dental.2007.05.014 ↗