journal article·2025-01Open access

Adsorption‐Based Electrochemical Sensor Design for the Aqueous Detection of Paracetamol

Pieter J. De Smedt, Aline Lauwers, Philippe M. Vereecken, Dirk E. De Vos, Rob Ameloot

Advanced Engineering Materials· Volume 27· Issue 1

Abstract

This study investigates the critical role of adsorption in the development of electrochemical sensors, focusing on carbon (Vulcan XC72R, acetylene black, and graphite) and zeolite (high‐silica ZSM‐5 and all‐silica zeolite β) materials. Based on the paracetamol adsorption characteristics of these materials, an optimized disposable electrochemical sensor is created. This sensor exhibits a linear range of up to 5 μM and a remarkable detection limit of 150 nM (S/N = 3), ≈1000‐time improvement over the blank sensor. Moreover, paracetamol can be measured selectively because glucose has no adsorption affinity for the selected sensor materials. These findings underscore the significance of adsorption properties in sensor material selection in enhancing sensitivity and robustness against interfering species.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Electrochemical sensors and biosensors · Advanced Chemical Sensor Technologies · Electrochemical Analysis and Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Center For Membrane Separations, Adsorption, Catalysis and Spectroscopy (cMACS) KU Leuven Celestijnenlaan 200F, box 2454 3001 Leuven Belgium

Energy Department Imec Kapeldreef 75 3001 Leuven Belgium

Energyville Thor Park 8320 3600 Genk Belgium

Funding

FWO

References (56)

Show source-provided references
1. 10.1021/acssensors.0c0189410.1021/acssensors.0c01894 ↗
2. 10.1039/C3AY41855C10.1039/C3AY41855C ↗
3. 10.1007/s00604-015-1568-710.1007/s00604-015-1568-7 ↗
4. 10.1007/s00604-017-2540-510.1007/s00604-017-2540-5 ↗
5. 10.3390/ijerph19241694510.3390/ijerph192416945 ↗
6. 10.1016/j.jallcom.2020.15691110.1016/j.jallcom.2020.156911 ↗
7. 10.1016/j.talanta.2015.06.05210.1016/j.talanta.2015.06.052 ↗
8. 10.1016/j.talanta.2019.12025210.1016/j.talanta.2019.120252 ↗
9. 10.1016/j.snb.2020.12786610.1016/j.snb.2020.127866 ↗
10. 10.1002/adfm.20180732610.1002/adfm.201807326 ↗
11. 10.1016/j.microc.2020.10526210.1016/j.microc.2020.105262 ↗
12. 10.1149/2.002406jes10.1149/2.002406jes ↗
13. 10.1016/j.carbon.2017.12.02010.1016/j.carbon.2017.12.020 ↗
14. 10.1039/D2AY01964G10.1039/D2AY01964G ↗
15. 10.1021/acsomega.2c0364110.1021/acsomega.2c03641 ↗
16. 10.1007/s00604-021-04992-x10.1007/s00604-021-04992-x ↗
17. 10.1007/s10800-023-01875-210.1007/s10800-023-01875-2 ↗
18. 10.1021/am501991810.1021/am5019918 ↗
19. 10.1016/j.aca.2021.33899210.1016/j.aca.2021.338992 ↗
20. 10.1093/bjaceaccp/mkt04910.1093/bjaceaccp/mkt049 ↗
21. 10.1007/s11356-018-2517-x10.1007/s11356-018-2517-x ↗
22. 10.1007/s00253-012-4414-410.1007/s00253-012-4414-4 ↗
23. 10.1016/j.cbpc.2013.08.00510.1016/j.cbpc.2013.08.005 ↗
24. 10.1039/C6RA17466C10.1039/C6RA17466C ↗
25. 10.20964/2022.11.8210.20964/2022.11.82 ↗
26. 10.1016/j.bios.2013.02.04410.1016/j.bios.2013.02.044 ↗
27. 10.1016/0021-9797(69)90089-710.1016/0021-9797(69)90089-7 ↗
28. 10.1016/j.watres.2017.04.01410.1016/j.watres.2017.04.014 ↗
29. 10.1016/j.jhazmat.2010.08.05910.1016/j.jhazmat.2010.08.059 ↗
30. 10.1088/2053-1591/ab8fec10.1088/2053-1591/ab8fec ↗
31. 10.1002/anie.20200295310.1002/anie.202002953 ↗
32. 10.1016/j.jece.2022.10814110.1016/j.jece.2022.108141 ↗
33. 10.1016/j.jpha.2020.11.00310.1016/j.jpha.2020.11.003 ↗
34. 10.1016/j.aca.2015.05.04410.1016/j.aca.2015.05.044 ↗
35. 10.1016/j.rinp.2021.10391110.1016/j.rinp.2021.103911 ↗
36. https://www.coatino.com/products/PR_52041345(accessed: 4th August 2024).
37. 10.1111/cote.1244610.1111/cote.12446 ↗
38. 10.1016/j.colsurfa.2022.12945010.1016/j.colsurfa.2022.129450 ↗
39. 10.1016/j.apsusc.2020.14876010.1016/j.apsusc.2020.148760 ↗
40. 10.1016/j.talanta.2007.07.03510.1016/j.talanta.2007.07.035 ↗
41. 10.1016/j.carbon.2015.02.05910.1016/j.carbon.2015.02.059 ↗
42. 10.1002/app.4453310.1002/app.44533 ↗
43. 10.1021/acs.analchem.0c0185710.1021/acs.analchem.0c01857 ↗
44. 10.1016/j.measurement.2019.10710310.1016/j.measurement.2019.107103 ↗
45. 10.3390/nano1207117310.3390/nano12071173 ↗
46. 10.1021/acsapm.0c0023910.1021/acsapm.0c00239 ↗
47. 10.1016/j.microc.2023.10845510.1016/j.microc.2023.108455 ↗
48. 10.1021/acsbiomaterials.2c0124810.1021/acsbiomaterials.2c01248 ↗
49. S.Sarkar M.Bhattacharya inThe 46th Annual Conf. of the IEEE Industrial Electronics Society (IECON 2020) Singapore2020.
50. 10.1371/journal.pone.002378310.1371/journal.pone.0023783 ↗
51. https://maciassensors.com/product/anapot‐usb‐potentiostat/(accessed: 15th December 2023).
52. https://maciassensors.com/differential‐pulse‐voltammetry/(accessed: 8th December 2023).
53. 10.1007/s00604-012-0923-110.1007/s00604-012-0923-1 ↗
54. 10.1149/1.271018410.1149/1.2710184 ↗
55. 10.1016/j.elecom.2003.10.01310.1016/j.elecom.2003.10.013 ↗
56. https://www.who.int/data/gho/indicator‐metadata‐registry/imr‐details/2380(accessed: 12th December 2023).